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    Slc50a1 solute carrier family 50 member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 295245, updated on 9-Dec-2024

    Summary

    Official Symbol
    Slc50a1provided by RGD
    Official Full Name
    solute carrier family 50 member 1provided by RGD
    Primary source
    RGD:1308478
    See related
    EnsemblRapid:ENSRNOG00000020554 AllianceGenome:RGD:1308478
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Rag1ap1; RGD1308478
    Summary
    Predicted to enable glucoside transmembrane transporter activity and sugar transmembrane transporter activity. Predicted to be involved in carbohydrate transport. Located in endomembrane system. Orthologous to human SLC50A1 (solute carrier family 50 member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 78.3), Adrenal (RPKM 76.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Slc50a1 in Genome Data Viewer
    Location:
    2q34
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176975744..176978124, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (174677985..174680366, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (188585118..188587498, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 46 Neighboring gene keratinocyte associated protein 2 Neighboring gene dolichyl-phosphate mannosyltransferase subunit 3, regulatory Neighboring gene ephrin A1 Neighboring gene uncharacterized LOC102550325

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables glucoside transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sugar transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sugar transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in carbohydrate transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in carbohydrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in glucoside transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endomembrane system IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    sugar transporter SWEET1
    Names
    RAG1-activating protein 1
    recombination activating gene 1 activating protein 1
    solute carrier family 50 (sugar efflux transporter), member 1
    solute carrier family 50 (sugar transporter), member 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106445.1NP_001099915.1  sugar transporter SWEET1 precursor

      See identical proteins and their annotated locations for NP_001099915.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473976
      UniProtKB/Swiss-Prot
      D3ZH22
      UniProtKB/TrEMBL
      A6J6E2
      Related
      ENSRNOP00000085247.2, ENSRNOT00000098754.2
      Conserved Domains (1) summary
      pfam03083
      Location:127213
      MtN3_slv; Sugar efflux transporter for intercellular exchange

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176975744..176978124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063281615.1XP_063137685.1  sugar transporter SWEET1 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZYT4