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    Slc41a3 solute carrier family 41, member 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 641603, updated on 9-Dec-2024

    Summary

    Symbol
    Slc41a3provided by RGD
    Full Name
    solute carrier family 41, member 3provided by RGD
    Primary source
    RGD:1589573
    See related
    EnsemblRapid:ENSRNOG00000045821 AllianceGenome:RGD:1589573
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable magnesium:sodium antiporter activity. Predicted to be involved in mitochondrial magnesium ion transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in plasma membrane. Orthologous to human SLC41A3 (solute carrier family 41 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 137.9), Adrenal (RPKM 137.1) and 8 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Slc41a3 in Genome Data Viewer
    Location:
    4q34
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (124666789..124711968)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (123109555..123154766)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (123467552..123513447, complement)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486813 Neighboring gene aldehyde dehydrogenase 1 family, member L1 Neighboring gene uncharacterized LOC134486815 Neighboring gene IQ motif and Sec7 domain ArfGEF 1 Neighboring gene uncharacterized LOC134486814 Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables inorganic cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables magnesium:sodium antiporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables magnesium:sodium antiporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables monoatomic cation transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in magnesium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial magnesium ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial magnesium ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in monoatomic cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier family 41 member 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037492.1NP_001032569.1  solute carrier family 41 member 3

      See identical proteins and their annotated locations for NP_001032569.1

      Status: PROVISIONAL

      Source sequence(s)
      BC104698
      UniProtKB/Swiss-Prot
      Q3SWT5
      UniProtKB/TrEMBL
      A0A8I6A7H0
      Related
      ENSRNOP00000065688.1, ENSRNOT00000073268.3
      Conserved Domains (1) summary
      pfam01769
      Location:80212
      MgtE; Divalent cation transporter

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      124666789..124711968
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063286656.1XP_063142726.1  solute carrier family 41 member 3 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A7H0
    2. XM_006236872.5XP_006236934.1  solute carrier family 41 member 3 isoform X1

      See identical proteins and their annotated locations for XP_006236934.1

      UniProtKB/TrEMBL
      A0A0G2K1G1, A0A8I6A7H0, A6IB88
      Related
      ENSRNOP00000071826.1, ENSRNOT00000080734.3
      Conserved Domains (1) summary
      pfam01769
      Location:106237
      MgtE; Divalent cation transporter
    3. XM_006236871.5XP_006236933.1  solute carrier family 41 member 3 isoform X1

      See identical proteins and their annotated locations for XP_006236933.1

      UniProtKB/TrEMBL
      A0A0G2K1G1, A0A8I6A7H0, A6IB88
      Related
      ENSRNOP00000087291.2, ENSRNOT00000120080.2
      Conserved Domains (1) summary
      pfam01769
      Location:106237
      MgtE; Divalent cation transporter
    4. XM_006236874.4XP_006236936.1  solute carrier family 41 member 3 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A7H0
      Conserved Domains (1) summary
      pfam01769
      Location:106213
      MgtE; Divalent cation transporter
    5. XM_063286655.1XP_063142725.1  solute carrier family 41 member 3 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K1G1, A0A8I6A7H0, A6IB88
    6. XM_006236878.5XP_006236940.1  solute carrier family 41 member 3 isoform X4

      See identical proteins and their annotated locations for XP_006236940.1

      Conserved Domains (1) summary
      pfam01769
      Location:202343
      MgtE; Divalent cation transporter
    7. XM_039108305.2XP_038964233.1  solute carrier family 41 member 3 isoform X3

      Related
      ENSRNOP00000108387.1, ENSRNOT00000146243.1
      Conserved Domains (1) summary
      pfam01769
      Location:269411
      MgtE; Divalent cation transporter
    8. XM_039108306.2XP_038964234.1  solute carrier family 41 member 3 isoform X5

      Conserved Domains (1) summary
      pfam01769
      Location:178320
      MgtE; Divalent cation transporter
    9. XM_006236877.4XP_006236939.1  solute carrier family 41 member 3 isoform X4

      See identical proteins and their annotated locations for XP_006236939.1

      Conserved Domains (1) summary
      pfam01769
      Location:202343
      MgtE; Divalent cation transporter
    10. XM_039108307.2XP_038964235.1  solute carrier family 41 member 3 isoform X6

      Conserved Domains (1) summary
      pfam01769
      Location:117259
      MgtE; Divalent cation transporter