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    Fkbp2 FKBP prolyl isomerase 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293702, updated on 27-Dec-2024

    Summary

    Official Symbol
    Fkbp2provided by RGD
    Official Full Name
    FKBP prolyl isomerase 2provided by RGD
    Primary source
    RGD:1560660
    See related
    AllianceGenome:RGD:1560660
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560660
    Summary
    Predicted to enable peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding and regulation of transcription by RNA polymerase II. Predicted to be active in endoplasmic reticulum. Orthologous to human FKBP2 (FKBP prolyl isomerase 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 65.7), Brain (RPKM 64.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Fkbp2 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (213596931..213599606, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (204167724..204170399, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (222232349..222235113, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene phospholipase C beta 3 Neighboring gene protein phosphatase 1, regulatory (inhibitor) subunit 14B Neighboring gene FKBP prolyl isomerase 2 like 1 Neighboring gene vascular endothelial growth factor B Neighboring gene DnaJ heat shock protein family (Hsp40) member C4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    peptidyl-prolyl cis-trans isomerase FKBP2
    Names
    FK506 binding protein 2
    NP_001127900.1
    NP_001127901.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134428.1NP_001127900.1  peptidyl-prolyl cis-trans isomerase FKBP2 precursor

      See identical proteins and their annotated locations for NP_001127900.1

      Status: VALIDATED

      Source sequence(s)
      BG669308, BI285619, H35224
      UniProtKB/TrEMBL
      A6HZK7, A6HZK8, D3ZZR9
      Conserved Domains (1) summary
      pfam00254
      Location:40132
      FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase
    2. NM_001134429.1NP_001127901.1  peptidyl-prolyl cis-trans isomerase FKBP2 precursor

      See identical proteins and their annotated locations for NP_001127901.1

      Status: VALIDATED

      Source sequence(s)
      BG669308, BI285619, H35224
      UniProtKB/TrEMBL
      A6HZK7, A6HZK8, D3ZZR9
      Conserved Domains (1) summary
      pfam00254
      Location:40132
      FKBP_C; FKBP-type peptidyl-prolyl cis-trans isomerase

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      213596931..213599606 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)