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    Sult1a1 sulfotransferase family 1A member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 83783, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sult1a1provided by RGD
    Official Full Name
    sulfotransferase family 1A member 1provided by RGD
    Primary source
    RGD:3767
    See related
    EnsemblRapid:ENSRNOG00000019342 AllianceGenome:RGD:3767
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Stm; Stp1; ASTIV; Mx-ST; PST-1; St1a1; Sult1a3
    Summary
    Enables 3'-phosphoadenosine 5'-phosphosulfate binding activity; aryl sulfotransferase activity; and identical protein binding activity. Involved in several processes, including 4-nitrophenol metabolic process; estrogen metabolic process; and sulfation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including breast cancer; gastrointestinal system cancer (multiple); lung cancer (multiple); reproductive organ cancer (multiple); and urinary bladder cancer. Orthologous to several human genes including SULT1A1 (sulfotransferase family 1A member 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Liver (RPKM 2372.3), Lung (RPKM 510.3) and 5 other tissues See more
    Orthologs
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    Genomic context

    See Sult1a1 in Genome Data Viewer
    Location:
    1q36
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (190702592..190706112, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (181272022..181276750, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (198100586..198104106, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483843 Neighboring gene SAGA complex associated factor 29 Neighboring gene developmental pluripotency associated 3 like 3 Neighboring gene SLX1 homolog B, structure-specific endonuclease subunit Neighboring gene bolA family member 2

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in 3'-phosphoadenosine 5'-phosphosulfate metabolic process  
    involved_in 4-nitrophenol metabolic process PubMed 
    involved_in catecholamine metabolic process PubMed 
    involved_in estrogen metabolic process PubMed 
    involved_in estrogen metabolic process  
    involved_in ethanol catabolic process  
    involved_in flavonoid metabolic process  
    involved_in regulation of blood pressure PubMed 
    involved_in response to activity PubMed 
    involved_in response to glucocorticoid PubMed 
    involved_in response to insecticide PubMed 
    involved_in sulfation  
    involved_in sulfation PubMed 
    acts_upstream_of_or_within sulfation  
    involved_in sulfation  
    involved_in thyroid hormone metabolic process  
    involved_in xenobiotic metabolic process PubMed 
    involved_in xenobiotic metabolic process  
    involved_in xenobiotic metabolic process PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm  

    General protein information

    Preferred Names
    sulfotransferase 1A1
    Names
    Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3
    Phenol sulfotransferase 1a1
    aryl sulfotransferase IV
    minoxidil sulfotransferase
    sulfokinase
    sulfotransferase family 1A, phenol-preferring, member 1
    sulfotransferase family, cytosolic, 1A, phenol preferring
    sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
    sulphotransferase family cytosolic 1A phenol-prefering member 1
    tyrosine-ester sulfotransferase
    NP_114022.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031834.2NP_114022.1  sulfotransferase 1A1

      See identical proteins and their annotated locations for NP_114022.1

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/Swiss-Prot
      P17988, Q548D2
      UniProtKB/TrEMBL
      A6I9A5, A6I9A6
      Related
      ENSRNOP00000026186.1, ENSRNOT00000026186.6
      Conserved Domains (1) summary
      pfam00685
      Location:34284
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      190702592..190706112 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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