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    Exoc3l1 exocyst complex component 3-like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291961, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Exoc3l1provided by RGD
    Official Full Name
    exocyst complex component 3-like 1provided by RGD
    Primary source
    RGD:1311132
    See related
    EnsemblRapid:ENSRNOG00000015641 AllianceGenome:RGD:1311132
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Exoc3l; RGD1311132
    Summary
    Predicted to enable SNARE binding activity. Predicted to be involved in exocyst localization; exocytosis; and peptide hormone secretion. Predicted to be located in secretory granule. Predicted to be part of exocyst. Orthologous to human EXOC3L1 (exocyst complex component 3 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 69.8), Lung (RPKM 54.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Exoc3l1 in Genome Data Viewer
    Location:
    19q11
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (50076761..50084278, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (33166836..33174371, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (37245269..37252789, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene phagophore assembly factor 1 Neighboring gene F-box and leucine-rich repeat protein 8 Neighboring gene heat shock transcription factor 4 Neighboring gene microtubule associated tyrosine carboxypeptidase 1 Neighboring gene nucleolar protein 3 Neighboring gene E2F transcription factor 4 Neighboring gene engulfment and cell motility 3 Neighboring gene microRNA 6318

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion. Saito T, et al. Biomed Res, 2008 Apr. PMID 18480549
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in exocytosis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in peptide hormone secretion ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of exocyst ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in secretory granule ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    exocyst complex component 3-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106178.2 → NP_001099648.1  exocyst complex component 3-like protein

      See identical proteins and their annotated locations for NP_001099648.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A6IYN5
      Related
      ENSRNOP00000105944.1, ENSRNOT00000021015.7
      Conserved Domains (1) summary
      pfam06046
      Location:193 → 726
      Sec6; Exocyst complex component Sec6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      50076761..50084278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017601222.3 → XP_017456711.1  exocyst complex component 3-like protein isoform X1

      UniProtKB/TrEMBL
      A6IYN5
      Conserved Domains (1) summary
      pfam06046
      Location:193 → 726
      Sec6; Exocyst complex component Sec6

    2. XM_017601219.3 → XP_017456708.1  exocyst complex component 3-like protein isoform X1

      UniProtKB/TrEMBL
      A6IYN5
      Conserved Domains (1) summary
      pfam06046
      Location:193 → 726
      Sec6; Exocyst complex component Sec6

    3. XM_063277910.1 → XP_063133980.1  exocyst complex component 3-like protein isoform X1

      UniProtKB/TrEMBL
      A6IYN5

    4. XM_017601223.3 → XP_017456712.1  exocyst complex component 3-like protein isoform X2

      Conserved Domains (1) summary
      pfam06046
      Location:154 → 687
      Sec6; Exocyst complex component Sec6

    5. XM_063277909.1 → XP_063133979.1  exocyst complex component 3-like protein isoform X1

    6. XM_063277911.1 → XP_063133981.1  exocyst complex component 3-like protein isoform X3

      Related
      ENSRNOP00000100064.1, ENSRNOT00000122488.1

    7. XM_006255461.5 → XP_006255523.1  exocyst complex component 3-like protein isoform X1

      See identical proteins and their annotated locations for XP_006255523.1

      UniProtKB/TrEMBL
      A6IYN5
      Conserved Domains (1) summary
      pfam06046
      Location:193 → 726
      Sec6; Exocyst complex component Sec6

    8. XM_006255460.4 → XP_006255522.1  exocyst complex component 3-like protein isoform X1

      See identical proteins and their annotated locations for XP_006255522.1

      UniProtKB/TrEMBL
      A6IYN5
      Conserved Domains (1) summary
      pfam06046
      Location:193 → 726
      Sec6; Exocyst complex component Sec6

    RNA

    1. XR_005496632.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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