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    Spats2 spermatogenesis associated, serine-rich 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300221, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Spats2provided by RGD
    Official Full Name
    spermatogenesis associated, serine-rich 2provided by RGD
    Primary source
    RGD:1304780
    See related
    EnsemblRapid:ENSRNOG00000052307 AllianceGenome:RGD:1304780
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human SPATS2 (spermatogenesis associated serine rich 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 74.7), Kidney (RPKM 63.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Spats2 in Genome Data Viewer
    Location:
    7q36
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (132159021..132232296)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (130280100..130353425)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (140806729..140880109)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene complement C1q like 4 Neighboring gene DnaJ heat shock protein family (Hsp40) member C22 Neighboring gene U1 spliceosomal RNA Neighboring gene potassium voltage-gated channel subfamily H member 3 Neighboring gene microspherule protein 1 Neighboring gene pre-mRNA processing factor 40 homolog B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Identification of a novel protein p59(scr), which is expressed at specific stages of mouse spermatogenesis. Senoo M, et al. Biochem Biophys Res Commun, 2002 Apr 12. PMID 11944913
    2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    spermatogenesis-associated serine-rich protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001395111.1 → NP_001382040.1  spermatogenesis-associated serine-rich protein 2

      Status: INFERRED

      Source sequence(s)
      JAXUCZ010000007
      UniProtKB/TrEMBL
      A0A8I6AE83, F1LX68
      Related
      ENSRNOP00000090802.1, ENSRNOT00000097746.2
      Conserved Domains (1) summary
      pfam07139
      Location:81 → 385
      DUF1387; Protein of unknown function (DUF1387)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      132159021..132232296
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039078932.2 → XP_038934860.1  spermatogenesis-associated serine-rich protein 2 isoform X2

      UniProtKB/TrEMBL
      F1LX68
      Related
      ENSRNOP00000094635.1, ENSRNOT00000101673.2
      Conserved Domains (1) summary
      pfam07139
      Location:50 → 354
      DUF1387; Protein of unknown function (DUF1387)

    2. XM_039078929.1 → XP_038934857.1  spermatogenesis-associated serine-rich protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AE83, F1LX68
      Conserved Domains (1) summary
      pfam07139
      Location:81 → 385
      DUF1387; Protein of unknown function (DUF1387)

    3. XM_039078931.1 → XP_038934859.1  spermatogenesis-associated serine-rich protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AE83, F1LX68
      Conserved Domains (1) summary
      pfam07139
      Location:81 → 385
      DUF1387; Protein of unknown function (DUF1387)

    4. XM_039078930.2 → XP_038934858.1  spermatogenesis-associated serine-rich protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AE83, F1LX68
      Conserved Domains (1) summary
      pfam07139
      Location:81 → 385
      DUF1387; Protein of unknown function (DUF1387)

    5. XM_063263385.1 → XP_063119455.1  spermatogenesis-associated serine-rich protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AE83, F1LX68

    6. XM_039078933.2 → XP_038934861.1  spermatogenesis-associated serine-rich protein 2 isoform X3

      Conserved Domains (1) summary
      pfam07139
      Location:57 → 207
      DUF1387; Protein of unknown function (DUF1387)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001191614.1: Suppressed sequence

      Description
      NM_001191614.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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