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    Tceanc transcription elongation factor A N-terminal and central domain containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 367782, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tceancprovided by RGD
    Official Full Name
    transcription elongation factor A N-terminal and central domain containingprovided by RGD
    Primary source
    RGD:1584894
    See related
    EnsemblRapid:ENSRNOG00000065918 AllianceGenome:RGD:1584894
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human TCEANC (transcription elongation factor A N-terminal and central domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 31.1), Thymus (RPKM 22.7) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tceanc in Genome Data Viewer
    Location:
    Xq13
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (31587207..31592694)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (27952539..27961038)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (29498762..29505494)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene EGF-like-domain, multiple 6 Neighboring gene stabilizer of axonemal microtubules like 1 Neighboring gene trafficking protein particle complex subunit 2 Neighboring gene RAB9A, member RAS oncogene family

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transcription elongation factor A N-terminal and central domain-containing protein
    Names
    transcription elongation factor A (SII) N-terminal and central domain containing

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109015.2 → NP_001102485.1  transcription elongation factor A N-terminal and central domain-containing protein

      See identical proteins and their annotated locations for NP_001102485.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A6K2H4, D4AEK4
      Conserved Domains (3) summary
      TIGR01385
      Location:6 → 350
      TFSII; transcription elongation factor S-II
      pfam07500
      Location:180 → 286
      TFIIS_M; Transcription factor S-II (TFIIS), central domain
      cl02609
      Location:297 → 350
      Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      31587207..31592694
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006256856.5 → XP_006256918.1  transcription elongation factor A N-terminal and central domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_006256918.1

      UniProtKB/TrEMBL
      A6K2H4, D4AEK4
      Related
      ENSRNOP00000107383.1, ENSRNOT00000139999.1
      Conserved Domains (3) summary
      TIGR01385
      Location:6 → 350
      TFSII; transcription elongation factor S-II
      pfam07500
      Location:180 → 286
      TFIIS_M; Transcription factor S-II (TFIIS), central domain
      cl02609
      Location:297 → 350
      Zn-ribbon; C-terminal zinc ribbon domain of RNA polymerase intrinsic transcript cleavage subunit
    Nucleotide Protein Strain
    Heading Accession and Version

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