Reep4 receptor accessory protein 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Reep4provided by RGD
Official Full Name: receptor accessory protein 4provided by RGD
Primary source: RGD:1306561
See related: EnsemblRapid:ENSRNOG00000011373 AllianceGenome:RGD:1306561
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1306561
Summary: Predicted to enable microtubule binding activity. Predicted to be involved in endoplasmic reticulum tubular network organization and mitotic nuclear membrane reassembly. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. Orthologous to human REEP4 (receptor accessory protein 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Lung (RPKM 121.1), Thymus (RPKM 75.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 15p11

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (52030022..52033229)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (45620317..45623524)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (52235283..52238490)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH129078 (e-PCR)
- UniSTS:212386

AU029006 (e-PCR)
- UniSTS:111784

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in endoplasmic reticulum tubular network organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic nuclear membrane reassembly	ISO Inferred from Sequence Orthology more info
involved_in mitotic nuclear membrane reassembly	ISS Inferred from Sequence or Structural Similarity more info
involved_in nuclear envelope organization	ISO Inferred from Sequence Orthology more info
involved_in nuclear envelope organization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in cytoplasmic microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in endoplasmic reticulum	ISS Inferred from Sequence or Structural Similarity more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum tubular network	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: receptor expression-enhancing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025279.1 → NP_001020450.1 receptor expression-enhancing protein 4

See identical proteins and their annotated locations for NP_001020450.1

Status: PROVISIONAL

Source sequence(s)

BC097957

UniProtKB/Swiss-Prot

Q4QQW1

UniProtKB/TrEMBL

A6HTL3

Related

ENSRNOP00000015169.4, ENSRNOT00000015169.8

Conserved Domains (2) summary

PRK11675
Location:211 → 243

PRK11675; LexA regulated protein; Provisional

pfam03134
Location:19 → 94

TB2_DP1_HVA22; TB2/DP1, HVA22 family