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    Rgs7bp regulator of G-protein signaling 7 binding protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294715, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rgs7bpprovided by RGD
    Official Full Name
    regulator of G-protein signaling 7 binding proteinprovided by RGD
    Primary source
    RGD:1309360
    See related
    EnsemblRapid:ENSRNOG00000013389 AllianceGenome:RGD:1309360
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    R7bp; RGD1309360
    Summary
    Predicted to be involved in G protein-coupled receptor signaling pathway and regulation of postsynaptic membrane potential. Located in axon; dendrite; and perikaryon. Orthologous to human RGS7BP (regulator of G protein signaling 7 binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 256.0), Lung (RPKM 38.1) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Rgs7bp in Genome Data Viewer
    Location:
    2q13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (37867698..37965587, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (36133944..36231505, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (35072081..35619085, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene SREK1-interacting protein 1 Neighboring gene shisa like 2B Neighboring gene trifunctional nucleotide phosphoesterase protein YfkN-like Neighboring gene ring finger protein 180 Neighboring gene small nucleolar RNA SNORA17

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Clone Names

    • MGC109386

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in axon PubMed 
    located_in cytoplasm  
    located_in cytoplasm  
    located_in dendritic shaft PubMed 
    located_in dendritic spine head PubMed 
    located_in glutamatergic synapse  
    is_active_in glutamatergic synapse  
    is_active_in neuron projection  
    is_active_in nucleus  
    located_in nucleus  
    located_in nucleus  
    located_in perikaryon PubMed 
    located_in plasma membrane  
    is_active_in postsynapse  
    is_active_in postsynapse  
    located_in postsynaptic density membrane  
    is_active_in postsynaptic density membrane  
    is_active_in presynapse  
    located_in presynaptic membrane  
    is_active_in presynaptic membrane  

    General protein information

    Preferred Names
    regulator of G-protein signaling 7-binding protein
    Names
    R7 binding protein
    R7 family-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012347.1NP_001012347.1  regulator of G-protein signaling 7-binding protein

      See identical proteins and their annotated locations for NP_001012347.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089977
      UniProtKB/Swiss-Prot
      Q5FVH8
      UniProtKB/TrEMBL
      A6I5G8
      Related
      ENSRNOP00000018058.7, ENSRNOT00000018058.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      37867698..37965587 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017590705.3XP_017446194.1  regulator of G-protein signaling 7-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A0H2UHK8
    2. XM_063281508.1XP_063137578.1  regulator of G-protein signaling 7-binding protein isoform X1

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