Zfp7 zinc finger protein 7 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: Zfp7provided by RGD
Full Name: zinc finger protein 7provided by RGD
Primary source: RGD:1310636
See related: AllianceGenome:RGD:1310636
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Znf7
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human ZNF7 (zinc finger protein 7). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Kidney (RPKM 52.1), Heart (RPKM 43.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (110479387..110499552)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (108598666..108615740)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (117948926..117957642)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: zinc finger protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001401065.1 → NP_001387994.1 zinc finger protein 7

Status: VALIDATED

Source sequence(s)

JAXUCZ010000007

UniProtKB/TrEMBL

F1LV88, F1M5S6

Conserved Domains (4) summary

smart00349
Location:4 → 64

KRAB; krueppel associated box

COG5048
Location:231 → 620

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:292 → 312

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:632 → 657

zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086025.1 Reference GRCr8

Range

110479387..110499552

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063263601.1 → XP_063119671.1 zinc finger protein 7 isoform X1

UniProtKB/TrEMBL

F1LV88, F1M5S6
XM_063263602.1 → XP_063119672.1 zinc finger protein 7 isoform X2
XM_063263604.1 → XP_063119674.1 zinc finger protein 7 isoform X3
XM_039079250.2 → XP_038935178.1 zinc finger protein 7 isoform X4

Conserved Domains (4) summary

smart00349
Location:3 → 62

KRAB; krueppel associated box

COG5048
Location:229 → 618

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:290 → 310

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:630 → 655

zf-H2C2_2; Zinc-finger double domain
XM_063263605.1 → XP_063119675.1 zinc finger protein 7 isoform X6
XM_063263603.1 → XP_063119673.1 zinc finger protein 7 isoform X3
XM_039079251.2 → XP_038935179.1 zinc finger protein 7 isoform X5

Conserved Domains (4) summary

COG5048
Location:199 → 588

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:260 → 280

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam13465
Location:600 → 625

zf-H2C2_2; Zinc-finger double domain

cl02581
Location:1 → 32

KRAB_A-box; KRAB (Kruppel-associated box) domain -A box