Gapt Grb2-binding adaptor protein, transmembrane [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gaptprovided by RGD
Official Full Name: Grb2-binding adaptor protein, transmembraneprovided by RGD
Primary source: RGD:1586621
See related: EnsemblRapid:ENSRNOG00000026989 AllianceGenome:RGD:1586621
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in B cell homeostasis and B cell proliferation involved in immune response. Predicted to be located in Golgi apparatus and plasma membrane. Orthologous to human GAPT (GRB2 binding adaptor protein, transmembrane). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Spleen (RPKM 55.7), Thymus (RPKM 10.6) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 2q14

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	2	NC_086020.1 (43660900..43665485, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	2	NC_051337.1 (41927533..41932120, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	2	NC_005101.4 (41869555..41874130, complement)

Chromosome 2 - NC_086020.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:488481 (e-PCR)
- UniSTS:488481

RH144143 (e-PCR)
- UniSTS:233389

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in B cell homeostasis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within B cell homeostasis	ISO Inferred from Sequence Orthology more info
involved_in B cell proliferation involved in immune response	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within B cell proliferation involved in immune response	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi apparatus	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein GAPT

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.