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    Zfp26 zinc finger protein 26 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 367033, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp26provided by RGD
    Official Full Name
    zinc finger protein 26provided by RGD
    Primary source
    RGD:1565847
    See related
    EnsemblRapid:ENSRNOG00000025937 AllianceGenome:RGD:1565847
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1565847
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF268 (zinc finger protein 268); ZNF544 (zinc finger protein 544); and ZNF699 (zinc finger protein 699). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 103.4), Spleen (RPKM 93.3) and 9 other tissues See more
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    Genomic context

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    See Zfp26 in Genome Data Viewer
    Location:
    8q13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (27235912..27261879, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (18959656..18985647, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (21444833..21466474, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 7 subfamily H member 7B Neighboring gene zinc finger protein 560 Neighboring gene U6 spliceosomal RNA Neighboring gene zinc finger protein 426 Neighboring gene zinc finger protein 266

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 26

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108995.2 → NP_001102465.2  zinc finger protein 26

      See identical proteins and their annotated locations for NP_001102465.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A0A0G2K2I4
      Related
      ENSRNOP00000037843.8, ENSRNOT00000038084.8
      Conserved Domains (3) summary
      smart00349
      Location:104 → 162
      KRAB; krueppel associated box
      COG5048
      Location:338 → 751
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:399 → 419
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      27235912..27261879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006242652.5 → XP_006242714.1  zinc finger protein 26 isoform X1

      See identical proteins and their annotated locations for XP_006242714.1

      UniProtKB/TrEMBL
      A0A0G2K2I4
      Conserved Domains (3) summary
      smart00349
      Location:104 → 162
      KRAB; krueppel associated box
      COG5048
      Location:338 → 751
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:399 → 419
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_039081831.2 → XP_038937759.1  zinc finger protein 26 isoform X2

      Related
      ENSRNOP00000072254.3, ENSRNOT00000078192.3
      Conserved Domains (3) summary
      smart00349
      Location:103 → 161
      KRAB; krueppel associated box
      COG5048
      Location:337 → 750
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:398 → 418
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_006242653.5 → XP_006242715.1  zinc finger protein 26 isoform X1

      See identical proteins and their annotated locations for XP_006242715.1

      UniProtKB/TrEMBL
      A0A0G2K2I4
      Conserved Domains (3) summary
      smart00349
      Location:104 → 162
      KRAB; krueppel associated box
      COG5048
      Location:338 → 751
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:399 → 419
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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