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    Cep19 centrosomal protein 19 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 192229, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cep19provided by RGD
    Official Full Name
    centrosomal protein 19provided by RGD
    Primary source
    RGD:621352
    See related
    EnsemblRapid:ENSRNOG00000024924 AllianceGenome:RGD:621352
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD621352
    Summary
    Predicted to be involved in microtubule anchoring at centrosome and vesicle targeting, trans-Golgi to periciliary membrane compartment. Predicted to be located in cilium and nucleoplasm. Predicted to be active in microtubule cytoskeleton. Orthologous to human CEP19 (centrosomal protein 19). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 283.7), Heart (RPKM 243.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Cep19 in Genome Data Viewer
    Location:
    11q22
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (82182868..82192134, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (68677869..68687117, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (71921713..71938335, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481090 Neighboring gene negative regulator of reactive oxygen species Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class X Neighboring gene small nucleolar RNA SNORA17 Neighboring gene p21 (RAC1) activated kinase 2 Neighboring gene SUMO specific peptidase 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in microtubule anchoring at centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in microtubule anchoring at centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in microtubule anchoring at centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule anchoring at centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vesicle targeting, trans-Golgi to periciliary membrane compartment ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centriole ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ciliary basal body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ciliary basal body ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cilium ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in spindle pole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle pole ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    centrosomal protein of 19 kDa
    Names
    testis specific protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138865.3NP_620220.2  centrosomal protein of 19 kDa

      See identical proteins and their annotated locations for NP_620220.2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6IRT5, A6IRT6, G3V974
      Related
      ENSRNOP00000038182.1, ENSRNOT00000037795.5
      Conserved Domains (1) summary
      pfam14933
      Location:18168
      CEP19; CEP19-like protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      82182868..82192134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008768697.4XP_008766919.1  centrosomal protein of 19 kDa isoform X1

      See identical proteins and their annotated locations for XP_008766919.1

      UniProtKB/TrEMBL
      A6IRT5, A6IRT6, G3V974
      Conserved Domains (1) summary
      pfam14933
      Location:18168
      CEP19; CEP19-like protein
    2. XM_008768696.4XP_008766918.1  centrosomal protein of 19 kDa isoform X1

      See identical proteins and their annotated locations for XP_008766918.1

      UniProtKB/TrEMBL
      A6IRT5, A6IRT6, G3V974
      Conserved Domains (1) summary
      pfam14933
      Location:18168
      CEP19; CEP19-like protein