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    Lamp5 lysosomal-associated membrane protein family, member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 362220, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lamp5provided by RGD
    Official Full Name
    lysosomal-associated membrane protein family, member 5provided by RGD
    Primary source
    RGD:1306991
    See related
    EnsemblRapid:ENSRNOG00000005457 AllianceGenome:RGD:1306991
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    LAMP-5; BAD-LAMP; RGD1306991
    Summary
    Predicted to be involved in establishment of protein localization to organelle and presynaptic modulation of chemical synaptic transmission. Predicted to be located in several cellular components, including endoplasmic reticulum-Golgi intermediate compartment membrane; endosome; and growth cone membrane. Predicted to be active in several cellular components, including GABA-ergic synapse; cytoplasmic vesicle; and lysosomal membrane. Orthologous to human LAMP5 (lysosomal associated membrane protein family member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward (RPKM 214.4) See more
    Orthologs
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    Genomic context

    See Lamp5 in Genome Data Viewer
    Location:
    3q36
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (143825197..143837699)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (123372462..123384973)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (129012677..129031522)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486450 Neighboring gene phospholipase C, beta 4 Neighboring gene U6 spliceosomal RNA Neighboring gene p21 (RAC1) activated kinase 5 Neighboring gene small Cajal body-specific RNA 4 like 2 Neighboring gene uncharacterized LOC134486160

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Items 1 - 20 of 24
    Component Evidence Code Pubs
    is_active_in GABA-ergic synapse  
    located_in cytoplasmic vesicle membrane  
    located_in cytoplasmic vesicle membrane  
    located_in dendrite membrane  
    located_in dendrite membrane  
    located_in early endosome membrane  
    located_in early endosome membrane  
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane  
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane  
    located_in endosome membrane  
    located_in endosome membrane  
    located_in growth cone membrane  
    located_in growth cone membrane  
    located_in late endosome  
    is_active_in late endosome membrane  
    is_active_in lysosomal membrane  
    located_in lysosome  
    is_active_in plasma membrane  
    located_in plasma membrane  
    located_in plasma membrane  
    located_in recycling endosome membrane  
    located_in recycling endosome membrane  
    is_active_in synaptic vesicle  
    located_in synaptic vesicle membrane  
    Items 1 - 20 of 24

    General protein information

    Preferred Names
    lysosome-associated membrane glycoprotein 5
    Names
    LAMP family protein C20orf103 homolog
    brain and dendritic cell-associated LAMP
    brain-associated LAMP-like protein
    lysosome-associated membrane protein 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014183.2NP_001014205.1  lysosome-associated membrane glycoprotein 5 precursor

      See identical proteins and their annotated locations for NP_001014205.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/Swiss-Prot
      Q5PPI4
      Related
      ENSRNOP00000007274.5, ENSRNOT00000007274.9
      Conserved Domains (1) summary
      pfam01299
      Location:43213
      Lamp; Lysosome-associated membrane glycoprotein (Lamp)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      143825197..143837699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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