Klhl33 kelch-like family member 33 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Klhl33provided by RGD
Official Full Name: kelch-like family member 33provided by RGD
Primary source: RGD:2324282
See related: EnsemblRapid:ENSRNOG00000025868 AllianceGenome:RGD:2324282
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Orthologous to human KLHL33 (kelch like family member 33). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Muscle (RPKM 418.9) and Heart (RPKM 111.5) See more
Orthologs: human mouse all
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Genomic context

Location:: 15p14

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	15	NC_086033.1 (26579473..26589766, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	15	NC_051350.1 (24105923..24114445, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	15	NC_005114.4 (27811226..27819808, complement)

Chromosome 15 - NC_086033.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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General protein information

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Preferred Names: kelch-like protein 33

Names: kelch-like 33

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001433123.1 → NP_001420052.1 kelch-like protein 33

Status: VALIDATED

Source sequence(s)

JAXUCZ010000015

UniProtKB/TrEMBL

F1M601

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086033.1 Reference GRCr8

Range

26579473..26589766 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_002728195.7 → XP_002728241.3 kelch-like protein 33

Related

ENSRNOP00000035056.6, ENSRNOT00000032992.7

Conserved Domains (8) summary

smart00612
Location:583 → 629

Kelch; Kelch domain

smart00225
Location:234 → 330

BTB; Broad-Complex, Tramtrack and Bric a brac

smart00875
Location:335 → 435

BACK; BTB And C-terminal Kelch

TIGR03547
Location:513 → 765

muta_rot_YjhT; mutatrotase, YjhT family

sd00038
Location:572 → 615

Kelch; KELCH repeat [structural motif]

pfam00651
Location:224 → 326

BTB; BTB/POZ domain

pfam01344
Location:667 → 712

Kelch_1; Kelch motif

cl02518
Location:100 → 190

BTB; BTB/POZ domain