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    Actr10 actin related protein 10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299121, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Actr10provided by RGD
    Official Full Name
    actin related protein 10provided by RGD
    Primary source
    RGD:1306515
    See related
    EnsemblRapid:ENSRNOG00000007504 AllianceGenome:RGD:1306515
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in retrograde axonal transport of mitochondrion. Predicted to act upstream of or within microtubule-based movement. Predicted to be located in axon cytoplasm. Predicted to be part of dynactin complex. Orthologous to human ACTR10 (actin related protein 10). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 840.9), Muscle (RPKM 377.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Actr10 in Genome Data Viewer
    Location:
    6q24
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (95182082..95208325)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (89446141..89472350)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (93385457..93411605)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing 6 Neighboring gene small nucleolar RNA, C/D box 45 like 1 Neighboring gene transfer RNA alanine (anticodon AGC) 24 Neighboring gene transfer RNA lysine (anticodon CUU) 9 Neighboring gene proteasome 20S subunit alpha 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Dynactin. Schroer TA. Annu Rev Cell Dev Biol, 2004. PMID 15473859
    2. Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end. Eckley DM, et al. J Cell Biol, 1999 Oct 18. PMID 10525537, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC95127

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within microtubule-based movement ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in retrograde axonal transport of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in axon cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of dynactin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of dynactin complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    actin-related protein 10
    Names
    actin-related protein 10 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009602.1 → NP_001009602.1  actin-related protein 10

      See identical proteins and their annotated locations for NP_001009602.1

      Status: PROVISIONAL

      Source sequence(s)
      BC087143
      UniProtKB/TrEMBL
      F7F7Z6, Q5M9F7
      Related
      ENSRNOP00000085016.2, ENSRNOT00000103813.2
      Conserved Domains (1) summary
      cl17037
      Location:13 → 364
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      95182082..95208325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039111995.2 → XP_038967923.1  actin-related protein 10 isoform X1

      Conserved Domains (1) summary
      cl17037
      Location:13 → 181
      NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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