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    Polr2l RNA polymerase II, I and III subunit L [ Rattus norvegicus (Norway rat) ]

    Gene ID: 502374, updated on 9-Dec-2024

    Summary

    Symbol
    Polr2lprovided by RGD
    Full Name
    RNA polymerase II, I and III subunit Lprovided by RGD
    Primary source
    RGD:1566209
    See related
    AllianceGenome:RGD:1566209
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2L (RNA polymerase II, I and III subunit L). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 1119.4), Liver (RPKM 823.0) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Polr2l in Genome Data Viewer
    Location:
    1q41
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (205999607..206001615, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (196570051..196572060, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (214451966..214453974, complement)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene calcium release activated channel regulator 2B Neighboring gene CD151 molecule (Raph blood group) Neighboring gene tetraspanin 4 Neighboring gene chitinase domain containing 1

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase I complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of RNA polymerase II, core complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of RNA polymerase III complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerases I, II, and III subunit RPABC5
    Names
    DNA-directed RNA polymerases I, II, and III subunit RPABC5-like
    RNA polymerase II subunit L
    polymerase (RNA) II (DNA directed) polypeptide L
    polymerase (RNA) II subunit L
    NP_001137383.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001143911.1NP_001137383.1  DNA-directed RNA polymerases I, II, and III subunit RPABC5

      See identical proteins and their annotated locations for NP_001137383.1

      Status: VALIDATED

      Source sequence(s)
      AA924509, CB314321
      UniProtKB/TrEMBL
      A0A0G2JZT9, A6HY08
      Conserved Domains (1) summary
      pfam01194
      Location:159
      RNA_pol_N; RNA polymerases N / 8 kDa subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      205999607..206001615 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)