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    Prtfdc1 phosphoribosyl transferase domain containing 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291355, updated on 9-Dec-2024

    Summary

    Official Symbol
    Prtfdc1provided by RGD
    Official Full Name
    phosphoribosyl transferase domain containing 1provided by RGD
    Primary source
    RGD:1310177
    See related
    EnsemblRapid:ENSRNOG00000024874 AllianceGenome:RGD:1310177
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable protein homodimerization activity. Predicted to be involved in IMP salvage and purine ribonucleoside salvage. Predicted to be active in cytosol. Orthologous to human PRTFDC1 (phosphoribosyl transferase domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 88.2), Heart (RPKM 70.4) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Prtfdc1 in Genome Data Viewer
    Location:
    17q12.3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (88457872..88563109, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (83549608..83654517, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (87926242..88037040, complement)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 21 Neighboring gene uncharacterized LOC102550154 Neighboring gene uncharacterized LOC102550221 Neighboring gene enkurin, TRPC channel interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT enables hypoxanthine phosphoribosyltransferase activity  
    enables metal ion binding  
    enables nucleotide binding  
    enables protein homodimerization activity  
    Process Evidence Code Pubs
    NOT involved_in GMP catabolic process  
    involved_in IMP salvage  
    NOT involved_in guanine salvage  
    involved_in purine ribonucleoside salvage  
    Component Evidence Code Pubs
    is_active_in cytosol  

    General protein information

    Preferred Names
    phosphoribosyltransferase domain-containing protein 1
    NP_001099597.1
    XP_063132325.1
    XP_063132326.1
    XP_063132327.1
    XP_063132328.1
    XP_063132329.1
    XP_063132330.1
    XP_063132331.1
    XP_063132332.1
    XP_063132333.1
    XP_063132334.1
    XP_063132335.1
    XP_063132336.1
    XP_063132337.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106127.1 → NP_001099597.1  phosphoribosyltransferase domain-containing protein 1

      See identical proteins and their annotated locations for NP_001099597.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473990
      UniProtKB/TrEMBL
      A6JMB9, A6JMC0, B2RYS6, B2RYV9
      Related
      ENSRNOP00000110571.1, ENSRNOT00000121104.1
      Conserved Domains (1) summary
      cl00309
      Location:2 → 224
      PRTases_typeI; Phosphoribosyl transferase (PRT)-type I domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      88457872..88563109 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063276256.1 → XP_063132326.1  phosphoribosyltransferase domain-containing protein 1 isoform X2

    2. XM_063276255.1 → XP_063132325.1  phosphoribosyltransferase domain-containing protein 1 isoform X1

    3. XM_063276260.1 → XP_063132330.1  phosphoribosyltransferase domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A0G2K882
      Related
      ENSRNOP00000074506.2, ENSRNOT00000080193.3
    4. XM_063276261.1 → XP_063132331.1  phosphoribosyltransferase domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8I6GKT2, F7F5F6
      Related
      ENSRNOP00000112359.1, ENSRNOT00000168473.1
    5. XM_063276258.1 → XP_063132328.1  phosphoribosyltransferase domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      F7F5F6
    6. XM_063276259.1 → XP_063132329.1  phosphoribosyltransferase domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      F7F5F6
      Related
      ENSRNOP00000111721.1, ENSRNOT00000132788.1
    7. XM_063276266.1 → XP_063132336.1  phosphoribosyltransferase domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      F7F5F6
    8. XM_063276265.1 → XP_063132335.1  phosphoribosyltransferase domain-containing protein 1 isoform X11

    9. XM_063276264.1 → XP_063132334.1  phosphoribosyltransferase domain-containing protein 1 isoform X10

    10. XM_063276257.1 → XP_063132327.1  phosphoribosyltransferase domain-containing protein 1 isoform X3

    11. XM_063276263.1 → XP_063132333.1  phosphoribosyltransferase domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      F7F5F6
    12. XM_063276262.1 → XP_063132332.1  phosphoribosyltransferase domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A8I6AV37, F7F5F6
    13. XM_063276267.1 → XP_063132337.1  phosphoribosyltransferase domain-containing protein 1 isoform X13

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