Thsd7a thrombospondin type 1 domain containing 7A [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Thsd7aprovided by RGD
Official Full Name: thrombospondin type 1 domain containing 7Aprovided by RGD
Primary source: RGD:1566201
See related: EnsemblRapid:ENSRNOG00000030151 AllianceGenome:RGD:1566201
Gene type: protein coding
RefSeq status: INFERRED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1566201
Summary: Predicted to be involved in actin cytoskeleton organization. Predicted to be located in podocyte foot. Predicted to be active in plasma membrane. Orthologous to human THSD7A (thrombospondin type 1 domain containing 7A). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 67.1), Uterus (RPKM 52.1) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q21

Exon count:: 28

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (41427276..41865524, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (40461124..40899345, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (38658512..39103411, complement)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Correlation Between THSD7A Expression and Tumor Characteristics of Azoxymethane-Induced Colon Cancer Model in Rats.
Title: Correlation Between THSD7A Expression and Tumor Characteristics of Azoxymethane-Induced Colon Cancer Model in Rats.

Submit: New GeneRIF Correction

General gene information

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Markers

BE120568 (e-PCR)
- UniSTS:247356

d4rat152 (e-PCR)
- UniSTS:121971

BF399548 (e-PCR)
- UniSTS:247719

AU047130 (e-PCR)
- UniSTS:110811

D4Rat282 (e-PCR), detects polymorphism
- UniSTS:227823

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in actin cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in actin cytoskeleton organization	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info
located_in podocyte foot	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: thrombospondin type-1 domain-containing protein 7A

Names: thrombospondin, type I, domain containing 7A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001191970.2 → NP_001178899.2 thrombospondin type-1 domain-containing protein 7A precursor

Status: INFERRED

Source sequence(s)

JAXUCZ010000004

UniProtKB/TrEMBL

A6IDZ3, F1MA97

Related

ENSRNOP00000040000.6, ENSRNOT00000052063.7

Conserved Domains (2) summary

pfam19028
Location:184 → 235

TSP1_spondin; Spondin-like TSP1 domain

pfam19030
Location:1088 → 1151

TSP1_ADAMTS; Thrombospondin type 1 domain