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    Ppp1r1c protein phosphatase 1, regulatory (inhibitor) subunit 1C [ Rattus norvegicus (Norway rat) ]

    Gene ID: 499818, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ppp1r1cprovided by RGD
    Official Full Name
    protein phosphatase 1, regulatory (inhibitor) subunit 1Cprovided by RGD
    Primary source
    RGD:1562095
    See related
    EnsemblRapid:ENSRNOG00000024990 AllianceGenome:RGD:1562095
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562095
    Summary
    Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. Orthologous to human PPP1R1C (protein phosphatase 1 regulatory inhibitor subunit 1C). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 17.4), Muscle (RPKM 3.2) and 1 other tissue See more
    Orthologs
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    Genomic context

    See Ppp1r1c in Genome Data Viewer
    Location:
    3q24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (85023621..85126609)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (64616700..64719696)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (66673060..66783501)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691830 Neighboring gene ITPR interacting domain containing 2 Neighboring gene phosphodiesterase 1A Neighboring gene uncharacterized LOC134486399 Neighboring gene uncharacterized LOC103691836

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein phosphatase 1 regulatory subunit 1C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109200.2NP_001102670.1  protein phosphatase 1 regulatory subunit 1C

      See identical proteins and their annotated locations for NP_001102670.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A6HML7, D3ZSW2
      Related
      ENSRNOP00000035714.3, ENSRNOT00000034769.6
      Conserved Domains (1) summary
      pfam05395
      Location:284
      DARPP-32; Protein phosphatase inhibitor 1/DARPP-32

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      85023621..85126609
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)