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    Poc5 POC5 centriolar protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 294667, updated on 27-Dec-2024

    Summary

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    Official Symbol
    Poc5provided by RGD
    Official Full Name
    POC5 centriolar proteinprovided by RGD
    Primary source
    RGD:1310597
    See related
    EnsemblRapid:ENSRNOG00000018193 AllianceGenome:RGD:1310597
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310597
    Summary
    Predicted to be involved in eye photoreceptor cell development. Predicted to be located in centrosome; cytosol; and nucleoplasm. Predicted to be active in photoreceptor connecting cilium. Orthologous to human POC5 (POC5 centriolar protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 53.7), Thymus (RPKM 47.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Poc5 in Genome Data Viewer
    Location:
    2q12
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (29454392..29483468)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (27719745..27748805)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (27000303..27030646)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene nucleophosmin 1, pseudogene 10 Neighboring gene metal response element binding transcription factor 2, pseudogene 1 Neighboring gene ankyrin repeat and death domain containing 1B Neighboring gene DNA polymerase kappa

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Protein-protein interaction panel using mouse full-length cDNAs. Suzuki H, et al. Genome Res, 2001 Oct. PMID 11591653, Free PMC Article
    2. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. Jakobsen L, et al. EMBO J, 2011 Apr 20. PMID 21399614, Free PMC Article
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC114560

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in eye photoreceptor cell development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in centriole IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in photoreceptor connecting cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    centrosomal protein POC5
    Names
    POC5 centriolar protein homolog
    protein of centriole 5
    proteome of centriole 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025647.1 → NP_001020818.1  centrosomal protein POC5

      See identical proteins and their annotated locations for NP_001020818.1

      Status: VALIDATED

      Source sequence(s)
      BC097489
      UniProtKB/Swiss-Prot
      Q4V891
      Related
      ENSRNOP00000103023.1, ENSRNOT00000126447.1
      Conserved Domains (2) summary
      COG1196
      Location:175 → 354
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      PRK07003
      Location:371 → 543
      PRK07003; DNA polymerase III subunits gamma and tau; Validated

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      29454392..29483468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039101919.2 → XP_038957847.1  centrosomal protein POC5 isoform X1

      Related
      ENSRNOP00000070872.2, ENSRNOT00000087418.3
      Conserved Domains (1) summary
      PRK07003
      Location:271 → 443
      PRK07003; DNA polymerase III subunit gamma/tau
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V891.1 GenPept UniProtKB/Swiss-Prot:Q4V891

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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