Ndufb1 NADH:ubiquinone oxidoreductase subunit B1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ndufb1provided by RGD
Official Full Name: NADH:ubiquinone oxidoreductase subunit B1provided by RGD
Primary source: RGD:6487218
See related: EnsemblRapid:ENSRNOG00000088065 AllianceGenome:RGD:6487218
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: CI-MNLL
Summary: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Predicted to be located in mitochondrial inner membrane and nuclear speck. Predicted to be part of respiratory chain complex I. Orthologous to human NDUFB1 (NADH:ubiquinone oxidoreductase subunit B1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 1460.3), Muscle (RPKM 1177.4) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 6q32

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	6	NC_086024.1 (126880537..126888935, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	6	NC_051341.1 (121115649..121124055, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	6	NC_005105.4 (125861219..125870231, complement)

Chromosome 6 - NC_086024.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH143771 (e-PCR)
- UniSTS:233017

RH133633 (e-PCR)
- UniSTS:216916

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in mitochondrial respiratory chain complex I assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial respiratory chain complex I assembly	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	ISO Inferred from Sequence Orthology more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
located_in nuclear speck	ISO Inferred from Sequence Orthology more info
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info
part_of respiratory chain complex I	ISO Inferred from Sequence Orthology more info
part_of respiratory chain complex I	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: nADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

Names: Complex I-MNLL; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1; NADH-ubiquinone oxidoreductase MNLL subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001402546.1 → NP_001389475.1 nADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000006

UniProtKB/Swiss-Prot

P0DN35

UniProtKB/TrEMBL

A6JEJ6

Related

ENSRNOP00000109926.1, ENSRNOT00000153359.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086024.1 Reference GRCr8

Range

126880537..126888935 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_056985555.2 → XP_056841535.1 nADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 isoform X1

UniProtKB/Swiss-Prot

P0DN35

UniProtKB/TrEMBL

A6JEJ6