U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Znf740 zinc finger protein 740 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685834, updated on 9-Dec-2024

    Summary

    Official Symbol
    Znf740provided by RGD
    Official Full Name
    zinc finger protein 740provided by RGD
    Primary source
    RGD:1589052
    See related
    EnsemblRapid:ENSRNOG00000012192 AllianceGenome:RGD:1589052
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Orthologous to human ZNF740 (zinc finger protein 740). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 176.4), Kidney (RPKM 159.9) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Znf740 in Genome Data Viewer
    Location:
    7q36
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (135215413..135226189)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (133337038..133347594)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (143810033..143820459)

    Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene insulin-like growth factor binding protein 6 Neighboring gene sterol O-acyltransferase 2 Neighboring gene cysteine sulfinic acid decarboxylase Neighboring gene integrin subunit beta 7 Neighboring gene uncharacterized LOC134479582 Neighboring gene retinoic acid receptor, gamma Neighboring gene uncharacterized LOC134479581

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086025.1 Reference GRCr8

      Range
      135215413..135226189
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063264457.1XP_063120527.1  zinc finger protein 740 isoform X5

      UniProtKB/TrEMBL
      D4A538
    2. XM_008765873.3XP_008764095.1  zinc finger protein 740 isoform X5

      UniProtKB/TrEMBL
      D4A538
      Conserved Domains (2) summary
      sd00017
      Location:90110
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:102127
      zf-H2C2_2; Zinc-finger double domain
    3. XM_006242455.4XP_006242517.1  zinc finger protein 740 isoform X1

      UniProtKB/TrEMBL
      A0A8I5ZWP1, D4A538
      Conserved Domains (2) summary
      sd00017
      Location:115135
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:127152
      zf-H2C2_2; Zinc-finger double domain
    4. XM_008765871.3XP_008764093.1  zinc finger protein 740 isoform X4

      UniProtKB/TrEMBL
      D4A538
      Related
      ENSRNOP00000083176.2, ENSRNOT00000114738.2
      Conserved Domains (2) summary
      sd00017
      Location:103123
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:115140
      zf-H2C2_2; Zinc-finger double domain
    5. XM_063264458.1XP_063120528.1  zinc finger protein 740 isoform X7

    6. XM_008765870.3XP_008764092.1  zinc finger protein 740 isoform X2

      UniProtKB/TrEMBL
      D4A538
      Conserved Domains (2) summary
      sd00017
      Location:115135
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:127152
      zf-H2C2_2; Zinc-finger double domain
    7. XM_006242458.4XP_006242520.1  zinc finger protein 740 isoform X3

      UniProtKB/TrEMBL
      D4A538
      Conserved Domains (2) summary
      sd00017
      Location:103123
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:115140
      zf-H2C2_2; Zinc-finger double domain
    8. XM_008765875.3XP_008764097.1  zinc finger protein 740 isoform X6

      Conserved Domains (2) summary
      sd00017
      Location:6585
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:77102
      zf-H2C2_2; Zinc-finger double domain
    9. XM_039080395.1XP_038936323.1  zinc finger protein 740 isoform X8

      UniProtKB/TrEMBL
      A0A8I5ZQ97
      Related
      ENSRNOP00000080250.1, ENSRNOT00000097830.2
      Conserved Domains (2) summary
      sd00017
      Location:5373
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:6590
      zf-H2C2_2; Zinc-finger double domain

    RNA

    1. XR_010053536.1 RNA Sequence

    2. XR_010053537.1 RNA Sequence