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    Smtnl2 smoothelin-like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 679629, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Smtnl2provided by RGD
    Official Full Name
    smoothelin-like 2provided by RGD
    Primary source
    RGD:1585960
    See related
    EnsemblRapid:ENSRNOG00000015157 AllianceGenome:RGD:1585960
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in actin cytoskeleton organization. Predicted to be part of filamentous actin. Predicted to be active in microtubule organizing center. Orthologous to human SMTNL2 (smoothelin like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 656.3), Kidney (RPKM 173.5) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Smtnl2 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (57506873..57528050, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (57008322..57029505, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (58951845..58973020, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene probable serine/threonine-protein kinase drkD-like Neighboring gene XIAP associated factor 1 Neighboring gene F-box protein 39 Neighboring gene tektin 1 Neighboring gene uncharacterized LOC134480820 Neighboring gene MYB binding protein 1a Neighboring gene gamma-glutamyl transferase 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    smoothelin-like protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190998.1 → NP_001177927.1  smoothelin-like protein 2

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000010
      UniProtKB/TrEMBL
      D3ZUC1
      Related
      ENSRNOP00000020379.3, ENSRNOT00000020379.7
      Conserved Domains (2) summary
      PRK09039
      Location:8 → 84
      PRK09039; peptidoglycan -binding protein
      cd21261
      Location:347 → 453
      CH_SMTNL2; calponin homology (CH) domain found in smoothelin-like protein 2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      57506873..57528050 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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