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    Tspan3 tetraspanin 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 300733, updated on 9-Dec-2024

    Summary

    Official Symbol
    Tspan3provided by RGD
    Official Full Name
    tetraspanin 3provided by RGD
    Primary source
    RGD:1359444
    See related
    EnsemblRapid:ENSRNOG00000016474 AllianceGenome:RGD:1359444
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Tm4sf8
    Summary
    Predicted to be active in plasma membrane. Orthologous to human TSPAN3 (tetraspanin 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 983.9), Heart (RPKM 609.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Tspan3 in Genome Data Viewer
    Location:
    8q24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (65442100..65465961, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (56546067..56569815, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (60806848..60830448, complement)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene proline-serine-threonine phosphatase-interacting protein 1 Neighboring gene ribosomal protein L17, pseudogene 2 Neighboring gene pseudopodium-enriched atypical kinase 1 Neighboring gene iron-sulfur cluster assembly 2, pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    tetraspanin-3
    Names
    transmembrane 4 superfamily member 8
    NP_001005547.1
    XP_063121188.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005547.1NP_001005547.1  tetraspanin-3

      See identical proteins and their annotated locations for NP_001005547.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082102
      UniProtKB/TrEMBL
      A0A8I6GLN5, F7F5Z9, Q66H06
      Related
      ENSRNOP00000022419.4, ENSRNOT00000022419.6
      Conserved Domains (2) summary
      cd03163
      Location:104210
      TM4SF8_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF8_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...
      pfam00335
      Location:10237
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      65442100..65465961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063265118.1XP_063121188.1  tetraspanin-3 isoform X1