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    Erh ERH, mRNA splicing and mitosis factor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 681415, updated on 9-Dec-2024

    Summary

    Official Symbol
    Erhprovided by RGD
    Official Full Name
    ERH, mRNA splicing and mitosis factorprovided by RGD
    Primary source
    RGD:1595409
    See related
    EnsemblRapid:ENSRNOG00000004883 AllianceGenome:RGD:1595409
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable methyl-CpG binding activity. Predicted to be located in midbody and nucleus. Predicted to be part of methylosome. Orthologous to human ERH (ERH mRNA splicing and mitosis factor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 329.3), Spleen (RPKM 261.9) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Erh in Genome Data Viewer
    Location:
    6q24
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (106012255..106022521, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (100280933..100291200, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (104280390..104290905, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene exonuclease 3'-5' domain containing 2 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 16 Neighboring gene uncharacterized LOC134479446 Neighboring gene uncharacterized LOC134479447 Neighboring gene solute carrier family 39, member 9 Neighboring gene pleckstrin homology and coiled-coil domain containing D1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables methyl-CpG binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of methylosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    enhancer of rudimentary homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109442.2NP_001102912.1  enhancer of rudimentary homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I6AFK4, A0A8J8Y9X7, A6JDI9
      Related
      ENSRNOP00000059304.4, ENSRNOT00000066014.5
      Conserved Domains (1) summary
      pfam01133
      Location:22118
      ER; Enhancer of rudimentary
    2. NM_001419497.1NP_001406426.1  enhancer of rudimentary homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I5ZSD4, A0A8J8Y9X7, B2RYQ5, F1M4T3
      Related
      ENSRNOP00000081166.1, ENSRNOT00000100687.2

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      106012255..106022521 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)