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    C5h8orf88 similar to human chromosome 8 open reading frame 88 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 100912373, updated on 9-Dec-2024

    Summary

    Official Symbol
    C5h8orf88provided by RGD
    Official Full Name
    similar to human chromosome 8 open reading frame 88provided by RGD
    Primary source
    RGD:6487307
    See related
    EnsemblRapid:ENSRNOG00000007256 AllianceGenome:RGD:6487307
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable eukaryotic initiation factor 4E binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to be active in cytoplasm. Orthologous to human C8orf88 (chromosome 8 open reading frame 88). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 1368.6) and Brain (RPKM 58.8) See more
    Orthologs
    NEW
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    Genomic context

    See C5h8orf88 in Genome Data Viewer
    Location:
    5q13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (33127385..33152914)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (28330167..28355691)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (28480029..28505430)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene OTU deubiquitinase 6B Neighboring gene phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 Neighboring gene N-terminal EF-hand calcium binding protein 1 Neighboring gene ferritin light chain 1 pseudogene Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    similar to human chromosome 8 open reading frame 88; uncharacterized protein C8orf88 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001431986.1NP_001418915.1  similar to human chromosome 8 open reading frame 88 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
    2. NM_001431987.1NP_001418916.1  similar to human chromosome 8 open reading frame 88 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8L2Q4C3
    3. NM_001431988.1NP_001418917.1  similar to human chromosome 8 open reading frame 88 isoform c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6IIA1
    4. NM_001431989.1NP_001418918.1  similar to human chromosome 8 open reading frame 88 isoform c

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6IIA1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      33127385..33152914
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_056985544.2XP_056841524.1  uncharacterized protein C8orf88 homolog isoform X1

      Related
      ENSRNOP00000100605.1, ENSRNOT00000139380.1
    2. XM_056985545.2XP_056841525.1  uncharacterized protein C8orf88 homolog isoform X2

      Related
      ENSRNOP00000102971.1, ENSRNOT00000162817.1
    3. XM_063261271.1XP_063117341.1  uncharacterized protein C8orf88 homolog isoform X2

    4. XM_063261270.1XP_063117340.1  uncharacterized protein C8orf88 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8L2Q4C3