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    Ncor2 nuclear receptor co-repressor 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360801, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ncor2provided by RGD
    Official Full Name
    nuclear receptor co-repressor 2provided by RGD
    Primary source
    RGD:1310293
    See related
    EnsemblRapid:ENSRNOG00000001004 AllianceGenome:RGD:1310293
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables chromatin binding activity; nuclear glucocorticoid receptor binding activity; and nuclear retinoid X receptor binding activity. Involved in several processes, including estrous cycle; lactation; and response to estradiol. Located in chromatin. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human NCOR2 (nuclear receptor corepressor 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 91.5), Spleen (RPKM 47.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Ncor2 in Genome Data Viewer
    Location:
    12q15
    Exon count:
    51
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (37127736..37289612)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (31466418..31628319)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (36871917..37033701)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481291 Neighboring gene scavenger receptor class B, member 1 Neighboring gene uncharacterized LOC120095963 Neighboring gene uncharacterized LOC120095965 Neighboring gene refilin A Neighboring gene zinc finger protein 664 Neighboring gene ribosomal protein L27 like 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator. Madauss KP, et al. Mol Endocrinol, 2007 May. PMID 17356170
    2. Exchange of a nuclear corepressor between NF-kappaB and CREB mediates inhibition of phosphoenolpyruvate carboxykinase transcription by NF-kappaB. Yan JH, et al. Chin Med J (Engl), 2010 Jan 20. PMID 20137375
    3. Regulation of the content of progesterone and estrogen receptors, and their cofactors SRC-1 and SMRT by the 26S proteasome in the rat brain during the estrous cycle. Villamar-Cruz O, et al. Brain Res Bull, 2006 Apr 14. PMID 16564422
    4. Expression and hormonal regulation of coactivator and corepressor genes. Misiti S, et al. Endocrinology, 1998 May. PMID 9564863
    5. Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha. Yan J, et al. Mol Endocrinol, 2007 Jul. PMID 17456789

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables Notch binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables enzyme activator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables enzyme activator activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables histone deacetylase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables nuclear glucocorticoid receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables nuclear receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables nuclear retinoic acid receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables nuclear retinoid X receptor binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell proliferation in forebrain ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cerebellum development IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in epidermis development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in establishment of skin barrier ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in estrous cycle IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within forebrain development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in gene expression ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within glucose homeostasis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within heart morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in lactation IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of androgen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within negative regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of miRNA transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within positive regulation of protein deacetylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of protein deacetylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein stabilization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in random inactivation of X chromosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in regulation of ketone metabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in response to estradiol IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within telencephalon development ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within type I pneumocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of white fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within white fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of histone deacetylase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of transcription repressor complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    nuclear receptor corepressor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108334.1 → NP_001101804.1  nuclear receptor corepressor 2

      See identical proteins and their annotated locations for NP_001101804.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473973
      UniProtKB/TrEMBL
      A6J0X3, D3ZXN9
      Conserved Domains (4) summary
      smart00717
      Location:610 → 655
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam00249
      Location:610 → 653
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:142 → 228
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:432 → 475
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      37127736..37289612
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006249305.5 → XP_006249367.1  nuclear receptor corepressor 2 isoform X24

      UniProtKB/TrEMBL
      D3ZXN9
      Conserved Domains (6) summary
      PHA03247
      Location:1917 → 2321
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:156 → 411
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG5259
      Location:539 → 649
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      pfam00249
      Location:614 → 657
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:141 → 229
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:432 → 475
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    2. XM_006249320.5 → XP_006249382.1  nuclear receptor corepressor 2 isoform X42

      UniProtKB/TrEMBL
      D3ZXN9
      Conserved Domains (4) summary
      smart00717
      Location:614 → 659
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      pfam00249
      Location:614 → 657
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:142 → 228
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:432 → 475
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    3. XM_017598397.3 → XP_017453886.1  nuclear receptor corepressor 2 isoform X44

      UniProtKB/TrEMBL
      A0A0G2JU91, D3ZXN9
      Related
      ENSRNOP00000001334.5, ENSRNOT00000001334.8

    4. XM_017598398.3 → XP_017453887.1  nuclear receptor corepressor 2 isoform X45

      UniProtKB/TrEMBL
      D3ZXN9
      Related
      ENSRNOP00000069011.3, ENSRNOT00000084236.3

    5. XM_063271518.1 → XP_063127588.1  nuclear receptor corepressor 2 isoform X25

      UniProtKB/TrEMBL
      D3ZXN9

    6. XM_039089593.2 → XP_038945521.1  nuclear receptor corepressor 2 isoform X43

      UniProtKB/TrEMBL
      D3ZXN9
      Conserved Domains (6) summary
      PHA03247
      Location:1757 → 2258
      PHA03247; large tegument protein UL36; Provisional
      COG5259
      Location:538 → 648
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      TIGR02169
      Location:159 → 404
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam00249
      Location:613 → 656
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:141 → 229
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:431 → 474
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    7. XM_039089594.2 → XP_038945522.1  nuclear receptor corepressor 2 isoform X46

      UniProtKB/TrEMBL
      A0A8I6AN60
      Conserved Domains (6) summary
      PHA03247
      Location:1757 → 2258
      PHA03247; large tegument protein UL36; Provisional
      COG5259
      Location:538 → 648
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      TIGR02169
      Location:159 → 404
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam00249
      Location:613 → 656
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:141 → 229
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:431 → 474
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    8. XM_063271525.1 → XP_063127595.1  nuclear receptor corepressor 2 isoform X33

      UniProtKB/TrEMBL
      A0A8I6GHM0

    9. XM_063271499.1 → XP_063127569.1  nuclear receptor corepressor 2 isoform X6

      UniProtKB/TrEMBL
      A0A8I6GHM0

    10. XM_063271502.1 → XP_063127572.1  nuclear receptor corepressor 2 isoform X9

      UniProtKB/TrEMBL
      A0A8I6GHM0

    11. XM_063271507.1 → XP_063127577.1  nuclear receptor corepressor 2 isoform X14

      UniProtKB/TrEMBL
      A0A8I6GHM0

    12. XM_063271513.1 → XP_063127583.1  nuclear receptor corepressor 2 isoform X20

      UniProtKB/TrEMBL
      A0A8I6GHM0

    13. XM_063271508.1 → XP_063127578.1  nuclear receptor corepressor 2 isoform X15

      UniProtKB/TrEMBL
      A0A8I6GHM0

    14. XM_063271519.1 → XP_063127589.1  nuclear receptor corepressor 2 isoform X26

      UniProtKB/TrEMBL
      A0A8I6GHM0

    15. XM_063271506.1 → XP_063127576.1  nuclear receptor corepressor 2 isoform X13

      UniProtKB/TrEMBL
      A0A8I6GHM0

    16. XM_063271514.1 → XP_063127584.1  nuclear receptor corepressor 2 isoform X21

      UniProtKB/TrEMBL
      A0A8I6GHM0

    17. XM_063271521.1 → XP_063127591.1  nuclear receptor corepressor 2 isoform X29

      UniProtKB/TrEMBL
      A0A8I6GHM0

    18. XM_063271517.1 → XP_063127587.1  nuclear receptor corepressor 2 isoform X23

      UniProtKB/TrEMBL
      A0A8I6GHM0

    19. XM_063271523.1 → XP_063127593.1  nuclear receptor corepressor 2 isoform X31

      UniProtKB/TrEMBL
      A0A8I6GHM0

    20. XM_063271524.1 → XP_063127594.1  nuclear receptor corepressor 2 isoform X32

      UniProtKB/TrEMBL
      A0A8I6GHM0

    21. XM_063271501.1 → XP_063127571.1  nuclear receptor corepressor 2 isoform X8

      UniProtKB/TrEMBL
      A0A8I6GHM0

    22. XM_063271515.1 → XP_063127585.1  nuclear receptor corepressor 2 isoform X22

      UniProtKB/TrEMBL
      A0A8I6GHM0

    23. XM_063271522.1 → XP_063127592.1  nuclear receptor corepressor 2 isoform X30

      UniProtKB/TrEMBL
      A0A8I6GHM0

    24. XM_063271498.1 → XP_063127568.1  nuclear receptor corepressor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I6GHM0

    25. XM_063271503.1 → XP_063127573.1  nuclear receptor corepressor 2 isoform X10

      UniProtKB/TrEMBL
      A0A8I6GHM0

    26. XM_063271509.1 → XP_063127579.1  nuclear receptor corepressor 2 isoform X16

      UniProtKB/TrEMBL
      A0A8I6GHM0

    27. XM_063271504.1 → XP_063127574.1  nuclear receptor corepressor 2 isoform X11

      UniProtKB/TrEMBL
      A0A8I6GHM0

    28. XM_063271511.1 → XP_063127581.1  nuclear receptor corepressor 2 isoform X18

      UniProtKB/TrEMBL
      A0A8I6GHM0

    29. XM_017598392.3 → XP_017453881.1  nuclear receptor corepressor 2 isoform X4

      UniProtKB/TrEMBL
      A0A8I6GHM0

    30. XM_063271512.1 → XP_063127582.1  nuclear receptor corepressor 2 isoform X19

      UniProtKB/TrEMBL
      A0A8I6GHM0

    31. XM_017598396.3 → XP_017453885.1  nuclear receptor corepressor 2 isoform X28

      UniProtKB/TrEMBL
      A0A8I6GHM0

    32. XM_039089589.2 → XP_038945517.1  nuclear receptor corepressor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8I6GHM0
      Conserved Domains (6) summary
      PHA03247
      Location:1741 → 2145
      PHA03247; large tegument protein UL36; Provisional
      COG5259
      Location:364 → 474
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      TIGR02169
      Location:5 → 283
      SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
      pfam00249
      Location:439 → 482
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:1 → 54
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:257 → 300
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    33. XM_017598391.3 → XP_017453880.1  nuclear receptor corepressor 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6GHM0

    34. XM_063271510.1 → XP_063127580.1  nuclear receptor corepressor 2 isoform X17

      UniProtKB/TrEMBL
      A0A8I6GHM0
      Related
      ENSRNOP00000089758.1, ENSRNOT00000104620.2

    35. XM_063271520.1 → XP_063127590.1  nuclear receptor corepressor 2 isoform X27

      UniProtKB/TrEMBL
      A0A8I6GHM0

    36. XM_063271505.1 → XP_063127575.1  nuclear receptor corepressor 2 isoform X12

      UniProtKB/TrEMBL
      A0A8I6GHM0

    37. XM_063271500.1 → XP_063127570.1  nuclear receptor corepressor 2 isoform X7

      UniProtKB/TrEMBL
      A0A8I6GHM0

    38. XM_063271497.1 → XP_063127567.1  nuclear receptor corepressor 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I6GHM0

    39. XM_063271527.1 → XP_063127597.1  nuclear receptor corepressor 2 isoform X35

    40. XM_063271528.1 → XP_063127598.1  nuclear receptor corepressor 2 isoform X36

    41. XM_039089591.2 → XP_038945519.1  nuclear receptor corepressor 2 isoform X24

      UniProtKB/TrEMBL
      D3ZXN9
      Conserved Domains (6) summary
      PHA03247
      Location:1917 → 2321
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:156 → 411
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG5259
      Location:539 → 649
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      pfam00249
      Location:614 → 657
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:141 → 229
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:432 → 475
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    42. XM_017598394.3 → XP_017453883.1  nuclear receptor corepressor 2 isoform X24

      UniProtKB/TrEMBL
      D3ZXN9
      Conserved Domains (6) summary
      PHA03247
      Location:1917 → 2321
      PHA03247; large tegument protein UL36; Provisional
      COG0419
      Location:156 → 411
      SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
      COG5259
      Location:539 → 649
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      pfam00249
      Location:614 → 657
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:141 → 229
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl21498
      Location:432 → 475
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    43. XM_063271526.1 → XP_063127596.1  nuclear receptor corepressor 2 isoform X34

      UniProtKB/TrEMBL
      A6J0X4

    44. XM_039089592.2 → XP_038945520.1  nuclear receptor corepressor 2 isoform X37

      UniProtKB/TrEMBL
      A6J0X4
      Conserved Domains (2) summary
      PHA03247
      Location:1307 → 1711
      PHA03247; large tegument protein UL36; Provisional
      pfam00249
      Location:19 → 47
      Myb_DNA-binding; Myb-like DNA-binding domain

    45. XM_063271529.1 → XP_063127599.1  nuclear receptor corepressor 2 isoform X38

      UniProtKB/TrEMBL
      A6J0X4

    46. XM_063271530.1 → XP_063127600.1  nuclear receptor corepressor 2 isoform X39

      UniProtKB/TrEMBL
      A6J0X4

    47. XM_063271531.1 → XP_063127601.1  nuclear receptor corepressor 2 isoform X40

      UniProtKB/TrEMBL
      A6J0X4

    48. XM_063271532.1 → XP_063127602.1  nuclear receptor corepressor 2 isoform X41

      UniProtKB/TrEMBL
      A6J0X4
    Nucleotide Protein Strain
    Heading Accession and Version

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