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    Timm17b translocase of inner mitochondrial membrane 17b [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317374, updated on 9-Dec-2024

    Summary

    Symbol
    Timm17bprovided by RGD
    Full Name
    translocase of inner mitochondrial membrane 17bprovided by RGD
    Primary source
    RGD:1561744
    See related
    EnsemblRapid:ENSRNOG00000063664 AllianceGenome:RGD:1561744
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1561744
    Summary
    Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Orthologous to human TIMM17B (translocase of inner mitochondrial membrane 17B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 407.9), Kidney (RPKM 153.2) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Timm17b in Genome Data Viewer
    Location:
    Xq12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (17268257..17275424, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (14596330..14603491, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (15441369..15448452, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene proprotein convertase subtilisin/kexin type 1 inhibitor Neighboring gene ribosomal protein S19, pseudogene 7 Neighboring gene polyglutamine binding protein 1 Neighboring gene solute carrier family 35 member A2

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    mitochondrial import inner membrane translocase subunit Tim17-B
    Names
    mitochondrial import inner membrane translocase subunit Tim17-B-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108249.1NP_001101719.1  mitochondrial import inner membrane translocase subunit Tim17-B

      See identical proteins and their annotated locations for NP_001101719.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      A0A8J8XD91, A6KP64
      Related
      ENSRNOP00000059538.3, ENSRNOT00000066373.5
      Conserved Domains (1) summary
      cl02381
      Location:1171
      Tim17; Tim17/Tim22/Tim23/Pmp24 family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      17268257..17275424 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063280051.1XP_063136121.1  mitochondrial import inner membrane translocase subunit Tim17-B isoform X1

      UniProtKB/TrEMBL
      A0A8J8XD91