B3gnt2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: B3gnt2provided by RGD
Official Full Name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2provided by RGD
Primary source: RGD:1310077
See related: EnsemblRapid:ENSRNOG00000009267 AllianceGenome:RGD:1310077
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: B3gnt1
Summary: Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; protein glycosylation; and sensory perception of smell. Predicted to be active in Golgi membrane. Orthologous to human B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 306.5), Spleen (RPKM 225.1) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14q22

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (101009682..101034507, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (96808473..96833674, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (107592336..107617189, complement)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

UniSTS:495936 (e-PCR)
- UniSTS:495936

B3gnt2 (e-PCR), detects polymorphism
- UniSTS:495936

AU049826 (e-PCR)
- UniSTS:146272

BE105706 (e-PCR)
- UniSTS:245889

RH130434 (e-PCR)
- UniSTS:213718

RH143416 (e-PCR)
- UniSTS:232663

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within axon guidance	ISO Inferred from Sequence Orthology more info
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within cellular response to leukemia inhibitory factor	ISO Inferred from Sequence Orthology more info
involved_in poly-N-acetyllactosamine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in poly-N-acetyllactosamine biosynthetic process	ISO Inferred from Sequence Orthology more info
involved_in protein O-linked glycosylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein glycosylation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within sensory perception of smell	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

Names: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1

NP_001100710.1

EC 2.4.1.149

XP_006251617.1

EC 2.4.1.149

XP_006251618.1

EC 2.4.1.149

XP_008768649.1

EC 2.4.1.149

XP_063129336.1

EC 2.4.1.149

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.