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    Ifi44 interferon-induced protein 44 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310969, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ifi44provided by RGD
    Official Full Name
    interferon-induced protein 44provided by RGD
    Primary source
    RGD:1310523
    See related
    EnsemblRapid:ENSRNOG00000022218 AllianceGenome:RGD:1310523
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in immune response. Predicted to act upstream of or within response to bacterium. Orthologous to human IFI44 (interferon induced protein 44). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 176.3), Adrenal (RPKM 160.0) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ifi44 in Genome Data Viewer
    Location:
    2q45
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (243286050..243303869, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (240626058..240643879, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (256897765..256915591, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene adhesion G protein-coupled receptor L4 Neighboring gene uncharacterized LOC102548445 Neighboring gene interferon-induced protein 44-like Neighboring gene prostaglandin F receptor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Impact of lactobacilli on orally acquired listeriosis. Archambaud C, et al. Proc Natl Acad Sci U S A, 2012 Oct 9. PMID 23012479, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within response to bacterium ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    interferon-induced protein 44

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107729.1 → NP_001101199.1  interferon-induced protein 44

      See identical proteins and their annotated locations for NP_001101199.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473952
      UniProtKB/TrEMBL
      A6HWI9, D3ZAF8
      Related
      ENSRNOP00000108205.1, ENSRNOT00000134859.1
      Conserved Domains (2) summary
      cd02019
      Location:183 → 236
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
      cl02144
      Location:28 → 146
      TLD; TLD

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      243286050..243303869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006233498.4 → XP_006233560.1  interferon-induced protein 44 isoform X2

      See identical proteins and their annotated locations for XP_006233560.1

      UniProtKB/TrEMBL
      B0BNB7, D3ZAF8
      Conserved Domains (2) summary
      cd02019
      Location:183 → 236
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
      cl02144
      Location:28 → 146
      TLD; TLD

    2. XM_006233497.4 → XP_006233559.1  interferon-induced protein 44 isoform X2

      See identical proteins and their annotated locations for XP_006233559.1

      UniProtKB/TrEMBL
      B0BNB7, D3ZAF8
      Conserved Domains (2) summary
      cd02019
      Location:183 → 236
      NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
      cl02144
      Location:28 → 146
      TLD; TLD

    3. XM_063281991.1 → XP_063138061.1  interferon-induced protein 44 isoform X1

      UniProtKB/TrEMBL
      A6HWI9, D3ZAF8
      Related
      ENSRNOP00000031735.6, ENSRNOT00000029990.7
    Nucleotide Protein Strain
    Heading Accession and Version

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