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    Slc16a13 solute carrier family 16, member 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287451, updated on 9-Dec-2024

    Summary

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    Symbol
    Slc16a13provided by RGD
    Full Name
    solute carrier family 16, member 13provided by RGD
    Primary source
    RGD:1359138
    See related
    AllianceGenome:RGD:1359138
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in carboxylic acid transmembrane transport. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in plasma membrane. Orthologous to human SLC16A13 (solute carrier family 16 member 13). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 160.6), Adrenal (RPKM 37.1) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Slc16a13 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (55424633..55436555, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (54925973..54937860, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56827591..56831324, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene asialoglycoprotein receptor 2 Neighboring gene C-type lectin domain containing 10A Neighboring gene solute carrier family 16, member 11 Neighboring gene uncharacterized LOC120095129 Neighboring gene BCL6B, transcription repressor Neighboring gene microRNA 497

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico. SIGMA Type 2 Diabetes Consortium, et al. Nature, 2014 Feb 6. PMID 24390345, Free PMC Article
    2. The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. Halestrap AP, et al. Pflugers Arch, 2004 Feb. PMID 12739169
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables monocarboxylic acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in monocarboxylic acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    monocarboxylate transporter 13
    Names
    MCT 13
    solute carrier family 16 (monocarboxylic acid transporters), member 13
    solute carrier family 16, member 13 (monocarboxylic acid transporter 13)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005530.1 → NP_001005530.1  monocarboxylate transporter 13

      See identical proteins and their annotated locations for NP_001005530.1

      Status: PROVISIONAL

      Source sequence(s)
      BC081902
      UniProtKB/Swiss-Prot
      Q66HE2
      UniProtKB/TrEMBL
      A0A8I5ZP31, A6HG29
      Conserved Domains (1) summary
      cd17423
      Location:13 → 392
      MFS_MCT11_13; Monocarboxylate transporters 11 and 13 of the Major Facilitator Superfamily of transporters

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      55424633..55436555 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063268655.1 → XP_063124725.1  monocarboxylate transporter 13 isoform X1

      UniProtKB/Swiss-Prot
      Q66HE2
      UniProtKB/TrEMBL
      A0A8I5ZP31, A6HG29

    2. XM_039085473.2 → XP_038941401.1  monocarboxylate transporter 13 isoform X1

      UniProtKB/Swiss-Prot
      Q66HE2
      UniProtKB/TrEMBL
      A0A8I5ZP31, A6HG29
      Conserved Domains (1) summary
      cd17423
      Location:13 → 392
      MFS_MCT11_13; Monocarboxylate transporters 11 and 13 of the Major Facilitator Superfamily of transporters

    3. XM_063268654.1 → XP_063124724.1  monocarboxylate transporter 13 isoform X1

      UniProtKB/Swiss-Prot
      Q66HE2
      UniProtKB/TrEMBL
      A0A8I5ZP31, A6HG29
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q66HE2.1 GenPept UniProtKB/Swiss-Prot:Q66HE2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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