Pdzrn4 PDZ domain containing RING finger 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Pdzrn4provided by RGD
Official Full Name: PDZ domain containing RING finger 4provided by RGD
Primary source: RGD:1308860
See related: EnsemblRapid:ENSRNOG00000022844 AllianceGenome:RGD:1308860
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Orthologous to human PDZRN4 (PDZ domain containing ring finger 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 87.9), Brain (RPKM 17.6) and 1 other tissue See more
Orthologs: human mouse all
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Genomic context

Location:: 7q35

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (125696448..125844965)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (123816961..123965491)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (133856101..134004250)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D15Roc10 (e-PCR)
- UniSTS:510483

D7Rat196 (e-PCR), detects polymorphism
- UniSTS:228144

D7RAT62 (e-PCR)
- UniSTS:122357

General protein information

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Preferred Names: PDZ domain-containing RING finger protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001108107.2 → NP_001101577.2 PDZ domain-containing RING finger protein 4

Status: VALIDATED

Source sequence(s)

JAXUCZ010000007

UniProtKB/TrEMBL

D3ZNV5

Related

ENSRNOP00000037998.5, ENSRNOT00000038686.7

Conserved Domains (2) summary

smart00228
Location:24 → 55

PDZ; Domain present in PSD-95, Dlg, and ZO-1/2

cd00992
Location:144 → 226

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...