Gipc3 GIPC PDZ domain containing family, member 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gipc3provided by RGD
Official Full Name: GIPC PDZ domain containing family, member 3provided by RGD
Primary source: RGD:1563255
See related: AllianceGenome:RGD:1563255
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1563255
Summary: Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 15. Orthologous to human GIPC3 (GIPC PDZ domain containing family member 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Heart (RPKM 6.3), Adrenal (RPKM 3.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q11

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (9026905..9034005)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (8374941..8383281)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (11245160..11253080)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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General protein information

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Preferred Names: PDZ domain-containing protein GIPC3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109282.2 → NP_001102752.1 PDZ domain-containing protein GIPC3

See identical proteins and their annotated locations for NP_001102752.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000007

UniProtKB/TrEMBL

A6K892

Conserved Domains (1) summary

cd00992
Location:95 → 168

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...