Rexo1 RNA exonuclease 1 homolog [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Rexo1provided by RGD
Official Full Name: RNA exonuclease 1 homologprovided by RGD
Primary source: RGD:1309872
See related: EnsemblRapid:ENSRNOG00000017916 AllianceGenome:RGD:1309872
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Tceb3bp1
Summary: Predicted to enable exonuclease activity. Predicted to be involved in rRNA 3'-end processing. Predicted to be located in nuclear body. Predicted to be active in nucleus. Orthologous to human REXO1 (RNA exonuclease 1 homolog). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 52.9), Testes (RPKM 47.6) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 7q11

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (9804740..9824717)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (9154050..9174035)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (12022268..12041660)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

AW050347 (e-PCR)
- UniSTS:180068

RH143425 (e-PCR)
- UniSTS:232672

RH129948 (e-PCR)
- UniSTS:213236

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables exonuclease activity	IBA Inferred from Biological aspect of Ancestor more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in rRNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in nuclear body	IEA Inferred from Electronic Annotation more info
located_in nuclear body	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: RNA exonuclease 1 homolog

Names: REX1, RNA exonuclease 1 homolog; transcription elongation factor B polypeptide 3 binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001012114.3 → NP_001012114.2 RNA exonuclease 1 homolog

Status: VALIDATED

Source sequence(s)

JAXUCZ010000007

UniProtKB/TrEMBL

A6K8J6, D3ZCX6

Related

ENSRNOP00000024080.5, ENSRNOT00000024080.8

Conserved Domains (2) summary

cd06145
Location:1037 → 1185

REX1_like; DEDDh 3'-5' exonuclease domain of RNA exonuclease 1, -3 and similar eukaryotic proteins

pfam15870
Location:778 → 938

EloA-BP1; ElonginA binding-protein 1