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    Pced1a PC-esterase domain containing 1A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296158, updated on 9-Dec-2024

    Summary

    Official Symbol
    Pced1aprovided by RGD
    Official Full Name
    PC-esterase domain containing 1Aprovided by RGD
    Primary source
    RGD:1308836
    See related
    EnsemblRapid:ENSRNOG00000021221 AllianceGenome:RGD:1308836
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam113a; RGD1308836
    Summary
    Orthologous to human PCED1A (PC-esterase domain containing 1A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 71.1), Spleen (RPKM 60.3) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Pced1a in Genome Data Viewer
    Location:
    3q36
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (138049747..138076107, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (117600958..117622992, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (122942178..122947171, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene EBF family member 4 Neighboring gene uncharacterized LOC129351010 Neighboring gene carboxypeptidase X (M14 family), member 1 Neighboring gene transmembrane 239 Neighboring gene VPS16 core subunit of CORVET and HOPS complexes Neighboring gene protein tyrosine phosphatase, receptor type, A Neighboring gene uncharacterized LOC134486445 Neighboring gene mitochondrial ribosomal protein S26

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    PC-esterase domain-containing protein 1A
    Names
    family with sequence similarity 113, member A
    protein FAM113A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399284.1NP_001386213.1  PC-esterase domain-containing protein 1A isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      F7FQ71
      Conserved Domains (1) summary
      cd01842
      Location:34266
      SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...
    2. NM_001399285.1NP_001386214.1  PC-esterase domain-containing protein 1A isoform a

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      F7FQ71
      Conserved Domains (1) summary
      cd01842
      Location:34266
      SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...
    3. NM_001399286.1NP_001386215.1  PC-esterase domain-containing protein 1A isoform b

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      Related
      ENSRNOP00000052666.4, ENSRNOT00000055810.5
      Conserved Domains (1) summary
      cl01053
      Location:11236
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      138049747..138076107 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039104578.2XP_038960506.1  PC-esterase domain-containing protein 1A isoform X2

      Conserved Domains (1) summary
      cl01053
      Location:64296
      SGNH_hydrolase; or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical ...
    2. XM_006235015.4XP_006235077.1  PC-esterase domain-containing protein 1A isoform X1

      See identical proteins and their annotated locations for XP_006235077.1

      UniProtKB/TrEMBL
      A0A0G2JW48, A6HQ89
      Related
      ENSRNOP00000069741.2, ENSRNOT00000082369.3
      Conserved Domains (1) summary
      cd01842
      Location:64296
      SGNH_hydrolase_like_5; SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site ...
    3. XM_063283331.1XP_063139401.1  PC-esterase domain-containing protein 1A isoform X3

      UniProtKB/TrEMBL
      Q5FVL5

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001012348.1: Suppressed sequence

      Description
      NM_001012348.1: This RefSeq was removed because the CDS was partial.