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    Abitram actin binding transcription modulator [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298018, updated on 9-Dec-2024

    Summary

    Official Symbol
    Abitramprovided by RGD
    Official Full Name
    actin binding transcription modulatorprovided by RGD
    Primary source
    RGD:1594560
    See related
    EnsemblRapid:ENSRNOG00000010532 AllianceGenome:RGD:1594560
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam206a
    Summary
    Predicted to enable actin filament binding activity and actin monomer binding activity. Predicted to be involved in dendrite morphogenesis; regulation of actin filament polymerization; and regulation of filopodium assembly. Predicted to be located in growth cone and nuclear speck. Predicted to be active in several cellular components, including dendrite; filopodium tip; and lamellipodium. Orthologous to human ABITRAM (actin binding transcription modulator). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 37.2), Adrenal (RPKM 35.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Abitram in Genome Data Viewer
    Location:
    5q24
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (76301054..76308140)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (71505848..71524224)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (73552952..73560240)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene actin-like 7a Neighboring gene elongator acetyltransferase complex subunit 1 Neighboring gene catenin alpha-like 1 Neighboring gene transmembrane protein 245 Neighboring gene microRNA 32

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables actin monomer binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables actin monomer binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in dendrite morphogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in dendrite morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of actin filament polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of actin filament polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of filopodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of filopodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in filopodium tip IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in filopodium tip ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in lamellipodium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein Abitram
    Names
    family with sequence similarity 206, member A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399504.1NP_001386433.1  protein Abitram

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A0A8I6AMD6, A6KDR6, D4AE08
      Related
      ENSRNOP00000014053.5, ENSRNOT00000014053.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      76301054..76308140
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)