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    Medag mesenteric estrogen-dependent adipogenesis [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360757, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Medagprovided by RGD
    Official Full Name
    mesenteric estrogen-dependent adipogenesisprovided by RGD
    Primary source
    RGD:1307396
    See related
    EnsemblRapid:ENSRNOG00000000906 AllianceGenome:RGD:1307396
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307396
    Summary
    Predicted to be involved in positive regulation of fat cell differentiation. Predicted to be active in cytoplasm. Orthologous to human MEDAG (mesenteric estrogen dependent adipogenesis). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Heart (RPKM 94.9), Adrenal (RPKM 94.3) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Medag in Genome Data Viewer
    Location:
    12p11
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (10649526..10670913, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (5613191..5634583, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (6711745..6730959, complement)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481257 Neighboring gene WD40 repeat domain 95 like Neighboring gene testis expressed 26 Neighboring gene uncharacterized LOC102551556 Neighboring gene ribosomal protein L28, pseudogene 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel genes of visceral adiposity: identification of mouse and human mesenteric estrogen-dependent adipose (MEDA)-4 gene and its adipogenic function. Zhang H, et al. Endocrinology, 2012 Jun. PMID 22510272
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in positive regulation of fat cell differentiation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    mesenteric estrogen-dependent adipogenesis protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398808.1 → NP_001385737.1  mesenteric estrogen-dependent adipogenesis protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      D3ZTT1
      Related
      ENSRNOP00000103199.1, ENSRNOT00000156087.1

    2. NM_001398809.1 → NP_001385738.1  mesenteric estrogen-dependent adipogenesis protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000012
      UniProtKB/TrEMBL
      A6K165
      Related
      ENSRNOP00000001205.6, ENSRNOT00000001205.9

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      10649526..10670913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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