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    Rell2 RELT-like 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361313, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rell2provided by RGD
    Official Full Name
    RELT-like 2provided by RGD
    Primary source
    RGD:1305276
    See related
    EnsemblRapid:ENSRNOG00000019575 AllianceGenome:RGD:1305276
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305276
    Summary
    Predicted to enable collagen binding activity. Predicted to be involved in positive regulation of cell-substrate adhesion and positive regulation of p38MAPK cascade. Predicted to be located in basement membrane. Orthologous to human RELL2 (RELT like 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 120.9), Kidney (RPKM 34.5) and 7 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rell2 in Genome Data Viewer
    Location:
    18p11
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (30041204..30045193)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (29789996..29793986)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (31094965..31098536)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene diaphanous-related formin 1 Neighboring gene uncharacterized LOC120098325 Neighboring gene histone deacetylase 3 Neighboring gene FCH and double SH3 domains 1 Neighboring gene ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 Neighboring gene uncharacterized LOC134483010

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Clone Names

    • MGC109265

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables collagen binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of cell-substrate adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within positive regulation of cell-substrate adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of p38MAPK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of p38MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of p38MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of p38MAPK cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in basement membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in extracellular matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014149.1NP_001014171.1  RELT-like protein 2

      See identical proteins and their annotated locations for NP_001014171.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089946
      UniProtKB/Swiss-Prot
      Q5FVJ4
      UniProtKB/TrEMBL
      A6J3D8, A6J3D9
      Related
      ENSRNOP00000026526.3, ENSRNOT00000026526.7
      Conserved Domains (1) summary
      pfam12606
      Location:2857
      RELT; tumor necrosis factor receptor superfamily member 19

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      30041204..30045193
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039096962.2XP_038952890.1  RELT-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A6J3E0