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    Vps37b VPS37B subunit of ESCRT-I [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288659, updated on 9-Dec-2024

    Summary

    Official Symbol
    Vps37bprovided by RGD
    Official Full Name
    VPS37B subunit of ESCRT-Iprovided by RGD
    Primary source
    RGD:1304576
    See related
    EnsemblRapid:ENSRNOG00000001086 AllianceGenome:RGD:1304576
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1304576
    Summary
    Predicted to enable calcium-dependent protein binding activity. Predicted to be involved in protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in endosome membrane; midbody; and plasma membrane. Predicted to be part of ESCRT I complex. Orthologous to human VPS37B (VPS37B subunit of ESCRT-I). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 166.1), Spleen (RPKM 105.9) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Vps37b in Genome Data Viewer
    Location:
    12q15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (38220973..38249935)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (32560047..32589015)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (37984790..38023369)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene ATP binding cassette subfamily B member 9 Neighboring gene uncharacterized LOC102552690 Neighboring gene keratin-associated protein 4-6-like Neighboring gene huntingtin interacting protein 1 related Neighboring gene coiled-coil domain containing 62

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    part_of ESCRT I complex  
    part_of ESCRT I complex  
    located_in cytoplasm  
    located_in endosome  
    located_in endosome membrane  
    located_in late endosome membrane  
    located_in midbody  
    located_in plasma membrane  

    General protein information

    Preferred Names
    vacuolar protein sorting-associated protein 37B
    Names
    VPS37B, ESCRT-I subunit
    vacuolar protein sorting 37 homolog B
    vacuolar protein sorting 37B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105928.1NP_001099398.1  vacuolar protein sorting-associated protein 37B

      See identical proteins and their annotated locations for NP_001099398.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473973
      UniProtKB/TrEMBL
      A6J118, D3ZU64
      Related
      ENSRNOP00000001445.6, ENSRNOT00000001445.7
      Conserved Domains (1) summary
      pfam07200
      Location:11152
      Mod_r; Modifier of rudimentary (Mod(r)) protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      38220973..38249935
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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