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    Ccdc74a coiled-coil domain containing 74A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680752, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ccdc74aprovided by RGD
    Official Full Name
    coiled-coil domain containing 74Aprovided by RGD
    Primary source
    RGD:1588214
    See related
    EnsemblRapid:ENSRNOG00000001876 AllianceGenome:RGD:1588214
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to several human genes including CCDC74A (coiled-coil domain containing 74A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 37.2), Testes (RPKM 32.6) and 9 other tissues See more
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    Genomic context

    See Ccdc74a in Genome Data Viewer
    Location:
    11q23
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (96860161..96864540, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (83355888..83360269, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (87547026..87554513)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S15, pseudogene 13 Neighboring gene mediator complex subunit 15 Neighboring gene ribosomal protein L34, pseudogene 2 Neighboring gene U6 spliceosomal RNA Neighboring gene sphingomyelin phosphodiesterase 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 74B
    Names
    coiled-coil domain-containing protein 74A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419901.1NP_001406830.1  coiled-coil domain-containing protein 74B isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      UniProtKB/TrEMBL
      A6JSK6, F1M8E1
      Related
      ENSRNOP00000002567.7, ENSRNOT00000002567.8
    2. NM_001419902.1NP_001406831.1  coiled-coil domain-containing protein 74B isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000011
      Related
      ENSRNOP00000112247.1, ENSRNOT00000151680.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      96860161..96864540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039088987.2XP_038944915.1  coiled-coil domain-containing protein 74B isoform X2

      Conserved Domains (1) summary
      pfam14917
      Location:48165
      CCDC74_C; Coiled coil protein 74, C terminal
    2. XM_039088985.2XP_038944913.1  coiled-coil domain-containing protein 74B isoform X1

      Conserved Domains (1) summary
      pfam14917
      Location:116233
      CCDC74_C; Coiled coil protein 74, C terminal
    3. XM_063270763.1XP_063126833.1  coiled-coil domain-containing protein 74B isoform X2