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    Lrch2 leucine rich repeats and calponin homology domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 680591, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrch2provided by RGD
    Official Full Name
    leucine rich repeats and calponin homology domain containing 2provided by RGD
    Primary source
    RGD:1590569
    See related
    EnsemblRapid:ENSRNOG00000029582 AllianceGenome:RGD:1590569
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Orthologous to human LRCH2 (leucine rich repeats and calponin homology domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 47.8), Uterus (RPKM 28.5) and 7 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Lrch2 in Genome Data Viewer
    Location:
    Xq34
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (115903760..115986569, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (111091728..111174225, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (118532396..118615845, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 5, group A, member 2, pseudogene 1 Neighboring gene interleukin 13 receptor subunit alpha 2 Neighboring gene small nucleolar RNA, H/ACA box 35B Neighboring gene heterogeneous nuclear ribonucleoprotein A3-like Neighboring gene leucine zipper protein 4 Neighboring gene heterogeneous nuclear ribonucleoprotein M, pseudogene 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    leucine-rich repeat and calponin homology domain-containing protein 2
    Names
    leucine-rich repeats and calponin homology (CH) domain containing 2
    leucine-rich repeats and calponin homology (CH) domain containing 2-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427706.1 → NP_001414635.1  leucine-rich repeat and calponin homology domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      D4A456
      Related
      ENSRNOP00000038957.3, ENSRNOT00000045463.6

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      115903760..115986569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039100174.2 → XP_038956102.2  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X2

      Related
      ENSRNOP00000111995.1, ENSRNOT00000125286.1

    2. XM_039100177.2 → XP_038956105.2  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X5

    3. XM_039100176.2 → XP_038956104.2  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X4

      Related
      ENSRNOP00000106274.1, ENSRNOT00000154977.1

    4. XM_006257439.5 → XP_006257501.2  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X3

    5. XM_039100175.2 → XP_038956103.2  leucine-rich repeat and calponin homology domain-containing protein 2 isoform X1

      Related
      ENSRNOP00000100293.1, ENSRNOT00000153081.1
    Nucleotide Protein Strain
    Heading Accession and Version

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