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    Stard9 StAR-related lipid transfer domain containing 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691920, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Stard9provided by RGD
    Official Full Name
    StAR-related lipid transfer domain containing 9provided by RGD
    Primary source
    RGD:1593360
    See related
    EnsemblRapid:ENSRNOG00000010050 AllianceGenome:RGD:1593360
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310448
    Summary
    Predicted to enable microtubule binding activity and microtubule motor activity. Predicted to be involved in spindle assembly. Predicted to be active in centriole; cytoplasm; and nucleus. Orthologous to human STARD9 (StAR related lipid transfer domain containing 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 195.6), Heart (RPKM 143.5) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Stard9 in Genome Data Viewer
    Location:
    3q35
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (128034866..128150493)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (107581097..107672746)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (112428361..112659558)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene leucine rich repeat containing 57 Neighboring gene HAUS augmin like complex subunit 2 Neighboring gene uncharacterized LOC120101914 Neighboring gene codanin 1 Neighboring gene tau tubulin kinase 2 Neighboring gene uncharacterized LOC134486141 Neighboring gene ubiquitin protein ligase E3 component n-recognin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. Torres JZ, et al. Cell, 2011 Dec 9. PMID 22153075, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables microtubule motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables microtubule motor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spindle assembly ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centriole IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in centriole ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    stAR-related lipid transfer protein 9
    Names
    START domain containing 9-like
    StAR-related lipid transfer (START) domain containing 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427830.2 → NP_001414759.1  stAR-related lipid transfer protein 9

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000003
      UniProtKB/TrEMBL
      A0A0G2K9Y3, D3Z9J4
      Related
      ENSRNOP00000075178.2, ENSRNOT00000079109.3

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      128034866..128150493
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001080099.8 → XP_001080099.5  stAR-related lipid transfer protein 9 isoform X4

      UniProtKB/TrEMBL
      D3Z9J4

    2. XM_017592209.3 → XP_017447698.1  stAR-related lipid transfer protein 9 isoform X1

      UniProtKB/TrEMBL
      D3Z9J4
      Conserved Domains (6) summary
      smart00129
      Location:3 → 391
      KISc; Kinesin motor, catalytic domain. ATPase
      cd00060
      Location:481 → 581
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd01365
      Location:2 → 391
      KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
      pfam07960
      Location:4150 → 4247
      CBP4; CBP4
      pfam16183
      Location:390 → 504
      Kinesin_assoc; Kinesin-associated
      cl14643
      Location:4378 → 4552
      SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

    3. XM_039106810.2 → XP_038962738.1  stAR-related lipid transfer protein 9 isoform X3

      UniProtKB/TrEMBL
      D3Z9J4
      Conserved Domains (5) summary
      COG0711
      Location:4209 → 4260
      AtpF; FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]
      cd00060
      Location:481 → 581
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd01365
      Location:2 → 391
      KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
      pfam16183
      Location:390 → 504
      Kinesin_assoc; Kinesin-associated
      cl14643
      Location:4378 → 4521
      SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

    4. XM_039106809.2 → XP_038962737.1  stAR-related lipid transfer protein 9 isoform X2

      UniProtKB/TrEMBL
      D3Z9J4
      Conserved Domains (5) summary
      COG0711
      Location:4209 → 4260
      AtpF; FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]
      cd00060
      Location:481 → 581
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      cd01365
      Location:2 → 391
      KISc_KIF1A_KIF1B; Kinesin motor domain, KIF1_like proteins
      pfam16183
      Location:390 → 504
      Kinesin_assoc; Kinesin-associated
      cl14643
      Location:4378 → 4525
      SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

    5. XM_063284596.1 → XP_063140666.1  stAR-related lipid transfer protein 9 isoform X5

      UniProtKB/TrEMBL
      D3Z9J4
      Related
      ENSRNOP00000103189.1, ENSRNOT00000164510.1

    6. XM_006234817.5 → XP_006234879.2  stAR-related lipid transfer protein 9 isoform X6

      UniProtKB/TrEMBL
      A0A8I6GKI2
      Conserved Domains (3) summary
      cd00060
      Location:7 → 87
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam07960
      Location:3656 → 3753
      CBP4; CBP4
      cl14643
      Location:3884 → 4058
      SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

    7. XM_039106814.2 → XP_038962742.1  stAR-related lipid transfer protein 9 isoform X8

      UniProtKB/TrEMBL
      A0A8I6GKI2
      Conserved Domains (2) summary
      COG0711
      Location:3356 → 3407
      AtpF; FoF1-type ATP synthase, membrane subunit b or b' [Energy production and conversion]
      cl14643
      Location:3525 → 3699
      SRPBCC; START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily

    8. XM_017592211.3 → XP_017447700.1  stAR-related lipid transfer protein 9 isoform X7

      UniProtKB/TrEMBL
      A0A8I6GKI2

    RNA

    1. XR_005502955.2 RNA Sequence

    2. XR_010064699.1 RNA Sequence

    3. XR_010064698.1 RNA Sequence

    4. XR_010064700.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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