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    Cryzl1 crystallin zeta like 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288256, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Cryzl1provided by RGD
    Official Full Name
    crystallin zeta like 1provided by RGD
    Primary source
    RGD:1310219
    See related
    EnsemblRapid:ENSRNOG00000028014 AllianceGenome:RGD:1310219
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable identical protein binding activity. Predicted to be located in early endosome. Orthologous to human CRYZL1 (crystallin zeta like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 115.6), Kidney (RPKM 47.1) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Cryzl1 in Genome Data Viewer
    Location:
    11q11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 11 NC_086029.1 (44419099..44464366, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 11 NC_051346.1 (30933140..30977936, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (31847741..31893042, complement)

    Chromosome 11 - NC_086029.1Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C28 Neighboring gene SON DNA and RNA binding protein Neighboring gene phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase Neighboring gene DNA replication fork stabilization factor DONSON Neighboring gene intersectin 1 Neighboring gene uncharacterized LOC134481057 Neighboring gene ATP synthase peripheral stalk subunit OSCP

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins. Hu YH, et al. BMC Genomics, 2006 Jun 16. PMID 16780588, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in early endosome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    quinone oxidoreductase-like protein 1
    Names
    crystallin, zeta (quinone reductase)-like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013044.1 → NP_001013062.1  quinone oxidoreductase-like protein 1

      See identical proteins and their annotated locations for NP_001013062.1

      Status: PROVISIONAL

      Source sequence(s)
      BC083853
      UniProtKB/TrEMBL
      A0A8I6A2M2, Q5XI39
      Related
      ENSRNOP00000031695.4, ENSRNOT00000033745.6
      Conserved Domains (2) summary
      cd05195
      Location:31 → 346
      enoyl_red; enoyl reductase of polyketide synthase
      COG0604
      Location:1 → 325
      Qor; NADPH:quinone reductase or related Zn-dependent oxidoreductase [Energy production and conversion, General function prediction only]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086029.1 Reference GRCr8

      Range
      44419099..44464366 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063270419.1 → XP_063126489.1  quinone oxidoreductase-like protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8I6A2M2

    2. XM_063270422.1 → XP_063126492.1  quinone oxidoreductase-like protein 1 isoform X6

    3. XM_063270421.1 → XP_063126491.1  quinone oxidoreductase-like protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8I6A2M2

    4. XM_006248045.5 → XP_006248107.1  quinone oxidoreductase-like protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8I6A2M2
      Conserved Domains (2) summary
      cd05195
      Location:31 → 308
      enoyl_red; enoyl reductase of polyketide synthase
      COG0604
      Location:1 → 287
      Qor; NADPH:quinone reductase or related Zn-dependent oxidoreductase [Energy production and conversion, General function prediction only]

    5. XM_063270420.1 → XP_063126490.1  quinone oxidoreductase-like protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8I6A2M2, A0A8I6A6J0

    6. XM_063270418.1 → XP_063126488.1  quinone oxidoreductase-like protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A2M2

    7. XM_063270423.1 → XP_063126493.1  quinone oxidoreductase-like protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8I6AIQ7
      Related
      ENSRNOP00000093304.1, ENSRNOT00000112118.2

    RNA

    1. XR_005491010.2 RNA Sequence

    2. XR_010055943.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

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