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    Gse1 Gse1 coiled-coil protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 307913, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gse1provided by RGD
    Official Full Name
    Gse1 coiled-coil proteinprovided by RGD
    Primary source
    RGD:1562686
    See related
    EnsemblRapid:ENSRNOG00000017489 AllianceGenome:RGD:1562686
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1562686
    Summary
    Human ortholog(s) of this gene implicated in stomach cancer. Orthologous to human GSE1 (Gse1 coiled-coil protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 82.9), Spleen (RPKM 47.0) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Gse1 in Genome Data Viewer
    Location:
    19q12
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (65182678..65538183)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (48274164..48629456)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (53799945..54153732)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene CBY1 interacting BAR domain containing 2 Neighboring gene uncharacterized LOC102551361 Neighboring gene uncharacterized LOC102551937 Neighboring gene uncharacterized LOC134483396 Neighboring gene 5S ribosomal RNA Neighboring gene similar to human chromosome 16 open reading frame 74 Neighboring gene GINS complex subunit 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. GSE1 predicts poor survival outcome in gastric cancer patients by SLC7A5 enhancement of tumor growth and metastasis. Ding K, et al. J Biol Chem, 2018 Mar 16. PMID 29367342, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    genetic suppressor element 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427026.1 → NP_001413955.1  genetic suppressor element 1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000019
      UniProtKB/TrEMBL
      A0A8I5ZMU3, A6IZM2, F1M4A7
      Related
      ENSRNOP00000023607.7, ENSRNOT00000023607.10

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      65182678..65538183
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017601449.3 → XP_017456938.2  genetic suppressor element 1 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4U2, A0A8I6AG34
      Conserved Domains (1) summary
      pfam12540
      Location:1439 → 1579
      DUF3736; Protein of unknown function (DUF3736)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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