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    Unc119b unc-119 lipid binding chaperone B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288702, updated on 9-Dec-2024

    Summary

    Official Symbol
    Unc119bprovided by RGD
    Official Full Name
    unc-119 lipid binding chaperone Bprovided by RGD
    Primary source
    RGD:1309359
    See related
    EnsemblRapid:ENSRNOG00000021725 AllianceGenome:RGD:1309359
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1309359
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in cilium assembly and lipoprotein transport. Predicted to be located in ciliary transition zone. Orthologous to human UNC119B (unc-119 lipid binding chaperone B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 217.1), Thymus (RPKM 188.4) and 9 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Unc119b in Genome Data Viewer
    Location:
    12q16
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 12 NC_086030.1 (47139492..47152115)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (41478808..41491432)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (47239663..47252286)

    Chromosome 12 - NC_086030.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102548245 Neighboring gene malectin Neighboring gene acyl-CoA dehydrogenase short chain Neighboring gene signal peptide peptidase like 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in lipoprotein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in lipoprotein transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nervous system development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in ciliary transition zone ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein unc-119 homolog B
    Names
    unc-119 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105934.1NP_001099404.1  protein unc-119 homolog B

      See identical proteins and their annotated locations for NP_001099404.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473973
      UniProtKB/TrEMBL
      A0A0G2K351, A6J1W7
      Related
      ENSRNOP00000072503.2, ENSRNOT00000077871.3
      Conserved Domains (1) summary
      pfam05351
      Location:89247
      GMP_PDE_delta; GMP-PDE, delta subunit

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086030.1 Reference GRCr8

      Range
      47139492..47152115
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)