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    Naa12 N(alpha)-acetyltransferase 12, NatA catalytic subunit [ Rattus norvegicus (Norway rat) ]

    Gene ID: 498890, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Naa12provided by RGD
    Official Full Name
    N(alpha)-acetyltransferase 12, NatA catalytic subunitprovided by RGD
    Primary source
    RGD:1560212
    See related
    EnsemblRapid:ENSRNOG00000057774 AllianceGenome:RGD:1560212
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1560212
    Summary
    Predicted to enable peptide-glutamate-alpha-N-acetyltransferase activity and peptide-serine-alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation. Predicted to be part of NatA complex. Orthologous to human NAA11 (N-alpha-acetyltransferase 11, NatA catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 305.3), Muscle (RPKM 291.1) and 9 other tissues See more
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    Genomic context

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    See Naa12 in Genome Data Viewer
    Location:
    18q12.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 18 NC_086036.1 (75934117..75940509)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 18 NC_051353.1 (73659139..73665531)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (76725253..76731645)

    Chromosome 18 - NC_086036.1Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P0 pseudogene Neighboring gene ribosome binding factor A Neighboring gene thioredoxin-like 4A Neighboring gene heat shock factor binding protein 1-like 1 Neighboring gene solute carrier family 66 member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC156819

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables peptide-glutamate-alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peptide-serine-alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of NatA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    N(alpha)-acetyltransferase 12, NatA catalytic subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077676.1 → NP_001071144.1  N(alpha)-acetyltransferase 12, NatA catalytic subunit

      See identical proteins and their annotated locations for NP_001071144.1

      Status: PROVISIONAL

      Source sequence(s)
      BC127540
      UniProtKB/TrEMBL
      A0JPQ5, A6K5G7, A6K5G8
      Related
      ENSRNOP00000099749.1, ENSRNOT00000144099.1
      Conserved Domains (2) summary
      COG0456
      Location:1 → 149
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
      pfam00583
      Location:47 → 122
      Acetyltransf_1; Acetyltransferase (GNAT) family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086036.1 Reference GRCr8

      Range
      75934117..75940509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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