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    Eif2s2 eukaryotic translation initiation factor 2 subunit beta [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296302, updated on 9-Dec-2024

    Summary

    Official Symbol
    Eif2s2provided by RGD
    Official Full Name
    eukaryotic translation initiation factor 2 subunit betaprovided by RGD
    Primary source
    RGD:735192
    See related
    EnsemblRapid:ENSRNOG00000017447 AllianceGenome:RGD:735192
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable mRNA binding activity; translation initiation factor activity; and translation initiation factor binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to act upstream of or within in utero embryonic development; male germ cell proliferation; and male gonad development. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2 complex. Predicted to be active in synapse. Orthologous to human EIF2S2 (eukaryotic translation initiation factor 2 subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Muscle (RPKM 723.9), Testes (RPKM 497.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Eif2s2 in Genome Data Viewer
    Location:
    3q41
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (163834846..163855733, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (143374652..143395460, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (150391455..150412179, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L38 like 6 Neighboring gene RALY heterogeneous nuclear ribonucleoprotein Neighboring gene Sec61 translocon subunit gamma, pseudogene 7 Neighboring gene small nucleolar RNA SNORA44 Neighboring gene agouti signaling protein Neighboring gene transfer RNA alanine (anticodon AGC) 28

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in cytoplasm  
    part_of eukaryotic translation initiation factor 2 complex  
    NOT located_in nucleus  
    is_active_in synapse  

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 2 subunit 2
    Names
    eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199380.1NP_955412.1  eukaryotic translation initiation factor 2 subunit 2

      See identical proteins and their annotated locations for NP_955412.1

      Status: PROVISIONAL

      Source sequence(s)
      BC062402
      UniProtKB/TrEMBL
      A0A8I6A6W5, A6KI11, F7FE42, Q6P685
      Related
      ENSRNOP00000081256.2, ENSRNOT00000110685.2
      Conserved Domains (1) summary
      smart00653
      Location:199308
      eIF2B_5; domain present in translation initiation factor eIF2B and eIF5

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      163834846..163855733 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283372.1XP_063139442.1  eukaryotic translation initiation factor 2 subunit 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A6W5
    2. XM_063283373.1XP_063139443.1  eukaryotic translation initiation factor 2 subunit 2 isoform X2

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