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    Dcakd dephospho-CoA kinase domain containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 360639, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Dcakdprovided by RGD
    Official Full Name
    dephospho-CoA kinase domain containingprovided by RGD
    Primary source
    RGD:1359211
    See related
    EnsemblRapid:ENSRNOG00000021682 AllianceGenome:RGD:1359211
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable dephospho-CoA kinase activity. Predicted to be involved in coenzyme A biosynthetic process. Orthologous to human DCAKD (dephospho-CoA kinase domain containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 56.2), Adrenal (RPKM 54.3) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Dcakd in Genome Data Viewer
    Location:
    10q32.1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (88457829..88489011, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (87957738..87989002, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (91095601..91126733, complement)

    Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L22 like 4 Neighboring gene complement C1q like 1 Neighboring gene N-myristoyltransferase 1 Neighboring gene phospholipase C, delta 3 Neighboring gene acyl-CoA binding domain containing 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC94233

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables dephospho-CoA kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables dephospho-CoA kinase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in coenzyme A biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    dephospho-CoA kinase domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007724.1 → NP_001007725.1  dephospho-CoA kinase domain-containing protein

      See identical proteins and their annotated locations for NP_001007725.1

      Status: PROVISIONAL

      Source sequence(s)
      BC079186
      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9
      Related
      ENSRNOP00000037891.3, ENSRNOT00000031498.5
      Conserved Domains (1) summary
      PRK00081
      Location:1 → 196
      coaE; dephospho-CoA kinase; Reviewed

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086028.1 Reference GRCr8

      Range
      88457829..88489011 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597406.3 → XP_017452895.1  dephospho-CoA kinase domain-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9
      Conserved Domains (1) summary
      PRK00081
      Location:1 → 196
      coaE; dephospho-CoA kinase; Reviewed

    2. XM_006247532.5 → XP_006247594.1  dephospho-CoA kinase domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_006247594.1

      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9
      Conserved Domains (1) summary
      PRK00081
      Location:1 → 196
      coaE; dephospho-CoA kinase; Reviewed

    3. XM_063269448.1 → XP_063125518.1  dephospho-CoA kinase domain-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9

    4. XM_063269449.1 → XP_063125519.1  dephospho-CoA kinase domain-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9

    5. XM_008768293.3 → XP_008766515.1  dephospho-CoA kinase domain-containing protein isoform X1

      See identical proteins and their annotated locations for XP_008766515.1

      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9
      Conserved Domains (1) summary
      PRK00081
      Location:1 → 196
      coaE; dephospho-CoA kinase; Reviewed

    6. XM_039086416.2 → XP_038942344.1  dephospho-CoA kinase domain-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9
      Conserved Domains (1) summary
      PRK00081
      Location:1 → 196
      coaE; dephospho-CoA kinase; Reviewed

    7. XM_063269451.1 → XP_063125521.1  dephospho-CoA kinase domain-containing protein isoform X1

      UniProtKB/Swiss-Prot
      Q6AY55
      UniProtKB/TrEMBL
      A6HJN9
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6AY55.1 GenPept UniProtKB/Swiss-Prot:Q6AY55

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