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    Wdcp WD repeat and coiled coil containing [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500623, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Wdcpprovided by RGD
    Official Full Name
    WD repeat and coiled coil containingprovided by RGD
    Primary source
    RGD:1563701
    See related
    AllianceGenome:RGD:1563701
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1563701
    Summary
    Predicted to enable kinase binding activity. Predicted to be involved in protein complex oligomerization. Orthologous to human WDCP (WD repeat and coiled coil containing). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 32.5), Brain (RPKM 16.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Wdcp in Genome Data Viewer
    Location:
    6q14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (33570145..33584985)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (27850684..27865540)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (29954639..29975758, complement)

    Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene tumor protein p53 inducible protein 3 Neighboring gene splicing factor 3B, subunit 6 Neighboring gene FKBP prolyl isomerase 1B Neighboring gene U6 spliceosomal RNA Neighboring gene MFSD2 lysolipid transporter B, sphingolipid Neighboring gene UBX domain protein 2A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of WDCP, a novel fusion partner for the anaplastic lymphoma tyrosine kinase ALK. Yokoyama N, et al. Biomed Rep, 2015 Jan. PMID 25469238, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein complex oligomerization ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    WD repeat and coiled-coil-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001399126.1 → NP_001386055.1  WD repeat and coiled-coil-containing protein

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000006
      UniProtKB/TrEMBL
      A0A8I6A4H8, M0R4L9
      Conserved Domains (1) summary
      pfam15390
      Location:2 → 672
      WDCP; WD repeat and coiled-coil-containing protein family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086024.1 Reference GRCr8

      Range
      33570145..33584985
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039113112.2 → XP_038969040.1  WD repeat and coiled-coil-containing protein isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4H8, M0R4L9
      Conserved Domains (1) summary
      pfam15390
      Location:2 → 672
      WDCP; WD repeat and coiled-coil-containing protein family

    2. XM_006239868.5 → XP_006239930.1  WD repeat and coiled-coil-containing protein isoform X1

      See identical proteins and their annotated locations for XP_006239930.1

      UniProtKB/TrEMBL
      A0A8I6A4H8, M0R4L9
      Conserved Domains (1) summary
      pfam15390
      Location:2 → 672
      WDCP; WD repeat and coiled-coil-containing protein family
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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